Evidence map›Paper›PMID 33212162›Full record

ArticleJournal of pharmaceutical sciences2021

Warp-Speed Covid-19 Vaccine Development: Beneficiaries of Maturation in Biopharmaceutical Technologies and Public-Private Partnerships.

Rodney J Y Ho

Abstract read
In one paragraph

Article in Journal of pharmaceutical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Observational
  6. Review
  7. COVID-19 and pregnancy: clinical outcomes; mechanisms, and vaccine efficacy.Translational research : the journal of laboratory and clinical medicine · 2023
    Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. The COVID-19 Vaccine: Why the Hesitancy?Journal of radiology nursing · 2021
    Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Rodney J Y HoDepartment of Pharmaceutics and Bioengineering, University of Washington, Seattle, WA 98206-7610, USA. Electronic address: rodneyho@uw.edu.

Funding

Targeted Long-acting Combination Antiretroviral Therapy (TLC-ART)UM1AI120176 · NIAID · UNIVERSITY OF WASHINGTON · PI COLLIER, ANN CORNWALL, HO, RODNEY J.Y. · 2015 to 2019
$15.0M
NextGen Long-acting and targeted combination ART for Children with HIVR33AI149665 · NIAID · UNIVERSITY OF WASHINGTON · PI HO, RODNEY J.Y. · 2022 to 2025
$4.1M
NextGen Long-acting and targeted combination ART for Children with HIVR61AI149665 · NIAID · UNIVERSITY OF WASHINGTON · PI HO, RODNEY J.Y., MELVIN, ANN JORNS · 2020 to 2021
$2.1M
NIAID NIH HHS R33 AI149665NIAID NIH HHS R61 AI149665NIAID NIH HHS UM1 AI120176
6 · The paper itself

Abstract

It is anticipated that effective vaccines will enable the resumption of social and economic normalcy. Current calls for masking, social distancing and other restrictive measures for the public-good are difficult to enforce and are unstainable. As ~2-4% of the 50 million SARS-CoV2-infected have succumbed to Covid-19, the US department of Health and Human Services has organized a public-private partnership called Operation Warp Speed (OWS) to develop, produce and deliver 300 million doses of safe and effective vaccines with a January 2021 target. While a majority of the 300+ Covid-19 vaccine candidates are in various stages of preclinical and early-stage clinical testing, 6 clinical candidates are supported with over 10 billion USD plus integrated resources under the OWS agenda. This unprecedented approach is investing in the manufacture of product candidates ahead of product approval. It is enabled by new gene and recombinant pharmaceutical platform technologies that are accelerating the clinical study timeline from ~10 to less than 1 year. It is anticipated that one or more of the 6 candidates under the OWS initiative will be safe, effective and provide a sustained immune response to prevent infection and disease progression. This way, social and economic activities could return to normalcy.

Indexed as

Public-Private Sector PartnershipsCOVID-19COVID-19 VaccinesDrug DevelopmentHumansSARS-CoV-2Technology, PharmaceuticalTime FactorsCOVID-19 VaccinesBiopharmaceuticsBiotechologyCovid-19FormulationGene therapySARS-CoV2Vaccines

Identifiers

PMID33212162
PMCPMC7671640

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.