ArticleImmunity2021
Competition for Active TGFβ Cytokine Allows for Selective Retention of Antigen-Specific Tissue- Resident Memory T Cells in the Epidermal Niche.
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Article in Immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.
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80citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
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Who cites it
80 citing papers in PubMed, 114 citations in OpenAlex.
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- Adaptive immunity in the pathogenesis of neurodegeneration.Nature immunology · 2026Review
- Temporal Dissection of TGF-β signaling reveals differential impact during female reproductive mucosal CD8 resident memory T cell differentiation.Mucosal immunology · 2026Article
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- Phenotypic Characterization and Prognostic Impact of CD103+ Tissue-Resident Memory T Cells in Diffuse Large B-cell Lymphoma.Cancer immunology research · 2026Article
- Clonal CD8Nature immunology · 2026Article
- CXCR6 promotes dermal CD8+ T cell survival and transition to long-term tissue residence.Journal of immunology (Baltimore, Md. : 1950) · 2026Article
- TGFβR Hyperactivation Drives CD103⁺/ITGB2⁺ TRM Cell Accumulation in High-Fat Diet-Exacerbated CIA.International journal of biological sciences · 2026Article
- Evolving role of CD8Frontiers in immunology · 2026Review
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- Immune control of functional memory CD8 T cells in normal-appearing vitiligo skin.Science advances · 2025Article
- Tissue-resident memory CD8Nature reviews. Gastroenterology & hepatology · 2025Review
- Regulatory T cells inhibit CD8bioRxiv : the preprint server for biology · 2025Article
- Allergic Contact Dermatitis: Immunopathology and Potential Therapeutic Strategies.Journal of clinical medicine · 2025Review
- CD226 identifies effector CD8Cell reports · 2025Article
- Engineering Universal Cancer Immunity: Non-Tumor-Specific mRNA Vaccines Trigger Epitope Spreading in Cold Tumors.Vaccines · 2025Review
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- Defining molecular circuits of CD8+ T cell responses in tissues during latent viral infection.The Journal of experimental medicine · 2025Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
15 authors at 5 institutions in 4 countries.
Toshiro HiraiDepartment of Dermatology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA. Electronic address: t-hirai@biken.osaka-u.ac.jp.
Yi YangDepartment of Dermatology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China; The Third Xiangya Hospital, Central South University, Changsha, China.
Yukari ZenkeDepartment of Dermatology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Dermatology, St. Luke's International Hospital, Tokyo, Japan.
Haiyue LiDepartment of Dermatology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA; School of Medicine, Tsinghua University, No. 1 Tsinghua Yuan, Haidian District, Beijing 100084, China.
Virendra K ChaudhriCenter for Systems Immunology and the Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.
Jacinto S De La Cruz DiazDepartment of Dermatology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Paul Yifan ZhouDepartment of Dermatology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Breanna Anh-Thu NguyenDepartment of Dermatology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Laurent BartholinTGF-b & Pancreatic Cancer Lab, Centre de Recherche en Cancérologie de Lyon (CRCL), Centre Léon Bérard, INSERM 1052, CNRS 5286, Université de Lyon, Université Claude Bernard Lyon 1, Lyon, France.
Creg J WorkmanDepartment of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA.
David W GriggsDepartment of Molecular Microbiology and Immunology, Saint Louis University, MO 63104, USA.
Dario A A VignaliDepartment of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA.
Harinder SinghCenter for Systems Immunology and the Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.
David MasopustDepartment of Microbiology and Immunology, Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA.
Daniel H KaplanDepartment of Dermatology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA. Electronic address: dankaplan@pitt.edu.
University of Pittsburgh · USCentral South University · CNSaint Louis University · USUniversité Claude Bernard Lyon 1 · FRUniversity of Minnesota · US
Funding
VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JOHN C. BYRD · 1988 to 2026
$158.0MSynergies among inhibitory receptors in tolerance, cancer & antiviral immunityP01AI108545 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Dario AA Vignali · 2015 to 2026
$30.8MAutoimmunity and Immunopathology Training ProgramT32AI089443 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHLOMCHIK, MARK J · 2010 to 2024
$6.6MRegulated Activation of Latent-TGFb Determines Leukocyte Occupancy of the Epidermal NicheR01AR060744 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAPLAN, DANIEL H · 2011 to 2020
$4.0MSpecial BD LSRFortessaTMS10OD011925 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BORGHESI, LISA · 2012 to 2012
$383kNCI NIH HHS P30 CA047904NIAID NIH HHS P01 AI108545NIAID NIH HHS T32 AI089443NIAMS NIH HHS R01 AR060744NIH HHS S10 OD011925
Abstract
Following antigen-driven expansion in lymph node, transforming growth factor-β (TGFβ) is required for differentiation of skin-recruited CD8
Indexed as
AnimalsBinding, CompetitiveBystander EffectCD8-Positive T-LymphocytesCellular MicroenvironmentClone CellsEpidermisImmunologic MemoryKeratinocytesMiceMice, Inbred C57BLOrgan SpecificityReceptors, Antigen, T-Cell, alpha-betaSignal TransductionT-Cell Antigen Receptor SpecificityT-Lymphocytes, RegulatoryReceptors, Antigen, T-Cell, alpha-betaTransforming Growth Factor betaantigenbystander Trmcompetitionkeratinocytesnicheresident memory T cellsskinTGFβα(v)β(6)α(v)β(8)
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.