ArticlePublic health reports (Washington, D.C. : 1974)
Differences in Opioid Overdose Mortality Rates Among Middle-Aged Adults by Race/Ethnicity and Sex, 1999-2018.
Article in Public health reports (Washington, D.C. : 1974). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 94 citations in OpenAlex.
- Local level of social inequity moderates implementation of evidence-based practices tailored to minoritized populations to reduce opioid overdose deaths.Journal of substance use and addiction treatment · 2026Trial
- Trends in opioid prescribing after shoulder arthroplasty in an integrated health system: an analysis across racial and ethnic groups.Journal of shoulder and elbow arthroplasty · 2026Article
- Opioid withdrawal engages a habenular subpopulation responsive to aversive states.bioRxiv : the preprint server for biology · 2026Article
- Examining Ethnic and Racial Variations in Opioid-related Hospitalizations Using Western U.S. Electronic Health Records.Journal of racial and ethnic health disparities · 2026Review
- Opioid overdose and cardiovascular disease-related mortality: a retrospective analysis using real-world data from the USA, 1999-2023.Frontiers in cardiovascular medicine · 2026Article
- Reach of Community-Selected Strategies to Reduce Opioid-Related Overdose Deaths in the HEALing Communities Study.Substance use & misuse · 2026Article
- Gender differences in opioid and stimulant poisoning in the central region of iran: a cross-sectional study.Scientific reports · 2025Article
- Spatial analysis of county-level determinants of overdose mortality in the United States using spatial machine learning.BMC public health · 2025Article
- Differences by race and ethnicity in drug use patterns, harm reduction practices and barriers to treatment among people who use drugs in Rhode Island.Harm reduction journal · 2025Article
- Occurrence of Opioid-Related Neurocognitive Symptoms Associated With Long-term Opioid Therapy.The Clinical journal of pain · 2025Article
- Disparities in fatal and non-fatal opioid-involved overdoses among middle-aged non-Hispanic Black Men and Women.Journal of racial and ethnic health disparities · 2025Article
- Racial/ethnic inequality in homelessness and drug overdose deaths in US States.Social psychiatry and psychiatric epidemiology · 2025Article
- Article
- State-level racial and ethnic disparities in buprenorphine treatment duration in the United States.The American journal on addictions · 2025Article
- Naloxone reversal of the cardiorespiratory depressant effects of opioids and mixtures of opioids and stimulants in rats.Frontiers in pharmacology · 2025Article
- Knowledge, experiences, and perceptions of medications for opioid use disorder among Black Kentuckians.Annals of medicine · 2024Article
- COVID-19 public health restrictions and opioid overdoes: a summative content analysis of emergency medical services records in three Texas counties.Substance abuse treatment, prevention, and policy · 2024Article
- Fentanyl and xylazine crisis: Crafting coherent strategies for opioid overdose prevention.World journal of psychiatry · 2024Article
- LatinX harm reduction capital, medication for opioid use disorder, and nonfatal overdose: A structural equation model analysis among people who use drugs in Massachusetts.Drug and alcohol dependence · 2024Article
- Disparities in Overdose Deaths: Looking Back at Larochelle and Colleagues' 2021 Paper.American journal of public health · 2024Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
objectivesThe types of opioids abused in the United States have changed from prescription opioids to heroin to fentanyl. However, the types of opioids abused may differ by demographic factors, especially among middle-aged adults. We examined national trends in opioid overdose mortality rates among middle-aged adults by race/ethnicity and sex.
methodsUsing 1999-2018 data from the Centers for Disease Control and Prevention Wide-ranging ONline Data for Epidemiologic Research database, we examined overdose mortality rates per 100 000 population in 2018 among adults aged 45-64 that involved natural and semisynthetic opioids, heroin, synthetic opioids (excluding methadone), and methadone. We tested for significant differences in mortality rates by race/ethnicity and sex. We plotted drug-specific trends by race/ethnicity and sex from 1999 to 2018.
resultsIn 2018, non-Hispanic White adults had the highest rates per 100 000 population of natural and semisynthetic overdose mortality (men: 8.7; women: 7.9;
conclusionsPolicy making should consider unique subgroup risks and alternative trajectories of opioid use other than people being prescribed opioids, developing opioid use disorder, subsequently moving to heroin, and then to fentanyl.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.