Evidence map›Paper›PMID 33211944›Full record

ArticleNeurospine2021

Retro-Odontoid Pseudotumor Formation in the Context of Various Acquired and Congenital Pathologies of the Craniovertebral Junction and Surgical Techniques.

Brian Fiani, Rebecca Houston, Imran Siddiqi, Mohammad Arshad, Taylor Reardon, Brandon Gilliland, Cyrus Davati, Athanasios Kondilis

Open access · diamondAbstract read
In one paragraph

Article in Neurospine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Exoscope-assisted far-lateral approach for a retro-odontoid pseudotumor in the lateral position without fusion: a technical case report.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  5. Article
  6. Postoperative changes in location and size of retro-odontoid pseudotumor after upper cervical fusion without decompression.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  7. Article
  8. Risk factors for the development of retro-odontoid pseudotumor in non-rheumatoid arthritis patients with atlantoaxial subluxation: a multicenter cross-sectional study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  9. Article
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  12. Retro-odontoid mass resolution analysis and timing following posterior cervical spinal fixation: 16-year paediatric neurosurgery experience in a single UK institute.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
  13. Review
  14. Pseudoachondroplasia associated with os odontoideum and retro-odontoid mass: case-based update.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Review
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Brian FianiDepartment of Neurosurgery, Desert Regional Medical Center, Palm Springs, CA, USA.
Rebecca HoustonDepartment of Neurosurgery, Desert Regional Medical Center, Palm Springs, CA, USA.
Imran SiddiqiWestern University of Health Sciences College of Osteopathic Medicine, Pomona, CA, USA.
Mohammad ArshadDepartment of Neurosurgery, Desert Regional Medical Center, Palm Springs, CA, USA.
Taylor ReardonUniversity of Pikeville, Kentucky College of Osteopathic Medicine, Pikeville, KY, USA.
Brandon GillilandAlabama College of Osteopathic Medicine, Dothan, AL, USA.
Cyrus DavatiNew York Institute of Technology College of Osteopathic Medicine, Glen Head, NY, USA.
Athanasios KondilisMichigan State University College of Osteopathic Medicine, East Lansing, MI, USA.
Desert Regional Medical Center · USAlabama College of Osteopathic Medicine · USMichigan State University · USNew York Institute of Technology · USUniversity of Pikeville · USWestern University of Health Sciences · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retro-odontoid pseudotumor formation consists of an abnormal growth of granulation tissue typically posterior to the odontoid process, resulting as a manifestation of atlantoaxial instability. This instability can occur as a result of conditions ranging from severe mechanical trauma to metabolic disease or autoimmune conditions such as rheumatoid arthritis. A pseudotumor may impinge on the spinal nerves or even the spinal cord and brainstem, manifesting symptoms from severe neck pain to cervicomedullary compression or myelopathy, and in some cases even sudden death. The objective of this review is to consolidate the findings in published case reports and relevant prior literature reviews regarding the formation of retro-odontoid pseudotumor. We address the pathophysiology involved in acquired and congenital pseudotumor formation, including those associated with rheumatoid arthritis (panni). Additionally, we discuss past and current operative techniques designed to curtail and ultimately regress a retro-odontoid pseudotumor and pannus. Surgical techniques that are addressed include ventral decompression (both transoral and transnasal), dorsal decompression, and indications for posterior instrumentation in pannus formation, particularly in cases that may be sufficiently treated in lieu of an anterior approach. Finally, we will examine the role of external orthoses as both a method of conservative treatment as well as a potential adjunct to the aforementioned surgical procedures.

Indexed as

Cervical spineCraniocervical junctionOdontoidPannusPseudotumorRetro-odontoid

Identifiers

PMID33211944
PMCPMC8021814
OpenAlexW3105238244

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.