Evidence map›Paper›PMID 33211706›Full record

ArticlePloS one2020

A pilot study of bladder voiding with real-time MRI and computational fluid dynamics.

Ryan Pewowaruk, David Rutkowski, Diego Hernando, Bunmi B Kumapayi, Wade Bushman, Alejandro Roldán-Alzate

Abstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Computational fluid dynamics of bladder voiding using 3D dynamic MRI.International journal for numerical methods in biomedical engineering · 2024
    Article
  9. Review
  10. Article
  11. Article
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  14. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Ryan PewowarukBiomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States of America.ORCID 0000-0003-1190-7196
David RutkowskiCardiovascular Research Center, University of Wisconsin-Madison, Madison, WI, United States of America.
Diego HernandoRadiology, University of Wisconsin-Madison, Madison, WI, United States of America.
Bunmi B KumapayiUrology, University of Wisconsin-Madison, Madison, WI, United States of America.
Wade BushmanUrology, University of Wisconsin-Madison, Madison, WI, United States of America.
Alejandro Roldán-AlzateBiomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States of America.ORCID 0000-0003-4149-4038

Funding

Training Program in Translational Cardiovascular Science (TPTCS)T32HL007936 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Lee Lochbaum Eckhardt, Gail A Robertson · 2001 to 2026
$11.6M
Wisconsin Multidisciplinary K12 Urologic Research Career Development ProgramK12DK100022 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI CHAD M. VEZINA · 2013 to 2026
$8.6M
NHLBI NIH HHS T32 HL007936NIDDK NIH HHS K12 DK100022
6 · The paper itself

Abstract

Lower urinary track symptoms (LUTS) affect many older adults. Multi-channel urodynamic studies provide information about bladder pressure and urinary flow but offer little insight into changes in bladder anatomy and detrusor muscle function. Here we present a novel method for real time MRI during bladder voiding. This was performed in a small cohort of healthy men and men with benign prostatic hyperplasia and lower urinary tract symptoms (BPH/LUTS) to demonstrate proof of principle; The MRI urodynamic protocol was successfully implemented, and bladder wall displacement and urine flow dynamics were calculated. Displacement analysis on healthy controls showed the greatest bladder wall displacement in the dome of the bladder while men with BPH/LUTS exhibited decreased and asymmetric bladder wall motion. Computational fluid dynamics of voiding showed men with BPH/LUTS had larger recirculation regions in the bladder. This study demonstrates the feasibility of performing MRI voiding studies and their potential to provide new insight into lower urinary tract function in health and disease.

Indexed as

AdultAgedCohort StudiesHumansHydrodynamicsLower Urinary Tract SymptomsMagnetic Resonance ImagingMaleMiddle AgedPilot ProjectsProstatic HyperplasiaUrinary BladderUrodynamics

Identifiers

PMID33211706
PMCPMC7676741

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.