Evidence map›Paper›PMID 33211615›Full record

ArticleJournal of women's health (2002)2021

Environmental Factors Involved in Maternal Morbidity and Mortality.

Abee L Boyles, Brandiese E Beverly, Suzanne E Fenton, Chandra L Jackson, Anne Marie Z Jukic, Vicki L Sutherland, Donna D Baird, Gwen W Collman, Darlene Dixon, Kelly K Ferguson and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of women's health (2002), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Abee L BoylesDivision of Extramural Research and Training, National Institute of Environmental Health Sciences, National Institutes of Health, U.S. Department of Health and Human Services, Durham, North Carolina, USA.
Brandiese E BeverlyNational Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, U.S. Department of Health and Human Services, Durham, North Carolina, USA.
Suzanne E FentonNational Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, U.S. Department of Health and Human Services, Durham, North Carolina, USA.
Chandra L JacksonEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, U.S. Department of Health and Human Services, Durham, North Carolina, USA.
Anne Marie Z JukicEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, U.S. Department of Health and Human Services, Durham, North Carolina, USA.
Vicki L SutherlandNational Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, U.S. Department of Health and Human Services, Durham, North Carolina, USA.
Donna D BairdEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, U.S. Department of Health and Human Services, Durham, North Carolina, USA.
Gwen W CollmanDivision of Extramural Research and Training, National Institute of Environmental Health Sciences, National Institutes of Health, U.S. Department of Health and Human Services, Durham, North Carolina, USA.
Darlene DixonNational Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, U.S. Department of Health and Human Services, Durham, North Carolina, USA.
Kelly K FergusonEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, U.S. Department of Health and Human Services, Durham, North Carolina, USA.
Janet E HallClinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health, U.S. Department of Health and Human Services, Durham, North Carolina, USA.
Elizabeth M MartinEpigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, U.S. Department of Health and Human Services, Durham, North Carolina, USA.
Thaddeus T SchugDivision of Extramural Research and Training, National Institute of Environmental Health Sciences, National Institutes of Health, U.S. Department of Health and Human Services, Durham, North Carolina, USA.
Alexandra J WhiteEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, U.S. Department of Health and Human Services, Durham, North Carolina, USA.
Kelly J ChandlerOffice of Policy, Planning, and Evaluation, National Institute of Environmental Health Sciences, National Institutes of Health, U.S. Department of Health and Human Services, Durham, North Carolina, USA.
National Institute of Environmental Health Sciences · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Mammary Gland as a Sensitive End Point to Effects of Endocrine DisruptorsZIAES102785 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI FENTON, SUZANNE · 2010 to 2021
$38.1M
Pathobiology Of Uterine Leiomyomas (fibroids)ZIAES021196 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI DIXON, DARLENE · 2009 to 2025
$31.7M
Toxicological Assessments for the Division of the National Toxicology ProgramZICES103316 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WALKER, NIGEL J · 2020 to 2021
$18.5M
Social and Environmental Determinants of Health EquityZIAES103325 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI JACKSON, CHANDRA · 2017 to 2025
$12.7M
Integrated Health Assessments for the Division of the National Toxicology ProgramZICES103317 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ROONEY, ANDREW · 2020 to 2021
$9.6M
Environment and Cancer EpidemiologyZIAES103332 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WHITE, ALEXANDRA · 2019 to 2025
$8.9M
Environmental influences on fertility and reproductive healthZIAES103333 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI JUKIC, ANNE MARIE · 2019 to 2025
$7.3M
Environmental Effects On FertilityZIAES049003 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI BAIRD, DONNA D. · 2009 to 2023
$3.3M
Intramural NIH HHS ZIA ES103325NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Nongenetic, environmental factors contribute to maternal morbidity and mortality through chemical exposures via air, water, soil, food, and consumer products. Pregnancy represents a particularly sensitive window of susceptibility during which physiological changes to every major organ system increase sensitivity to chemicals that can impact a woman's long-term health. Nonchemical stressors, such as low socioeconomic status, may exacerbate the effects of chemical exposures on maternal health. Racial/ethnic minorities are exposed disproportionately to both chemicals and nonchemical stressors, which likely contribute to the observed health disparities for maternal morbidities and mortality. Epidemiological studies linking exposures to adverse maternal health outcomes underscore the importance of environmental health impacts, and mechanistic studies in model systems reveal how chemicals perturb biological pathways and processes. Environmental stressors are associated with a variety of immediate maternal health impacts, including hypertensive disorders of pregnancy, fibroids, and infertility, as well as long-term maternal health impacts, such as higher risk of breast cancer and metabolic disorders. Identifying and reducing a pregnant woman's environmental exposures is not only beneficial to her offspring but also important to preserve her short- and long-term health.

Indexed as

Environmental ExposureWomen's HealthFemaleHumansMaternal HealthPregnancyair pollutionendocrine-disrupting chemicalenvironmental exposuresmaternal healthwindow of susceptibility

Identifiers

PMID33211615
PMCPMC7891208
OpenAlexW3099336981

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.