Evidence map›Paper›PMID 33211596›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2021

Intravenous sulforhodamine B reduces alveolar surface tension, improves oxygenation, and reduces ventilation injury in a respiratory distress model.

You Wu, Tam L Nguyen, Carrie E Perlman

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

You WuDepartment of Biomedical Engineering, Stevens Institute of Technology, Hoboken, New Jersey.
Tam L NguyenDepartment of Biomedical Engineering, Stevens Institute of Technology, Hoboken, New Jersey.
Carrie E PerlmanDepartment of Biomedical Engineering, Stevens Institute of Technology, Hoboken, New Jersey.
Stevens Institute of Technology · US

Funding

Improved ventilation of the edematous lungR01HL113577 · NHLBI · THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY · PI PERLMAN, CARRIE E · 2013 to 2021
$3.3M
NHLBI NIH HHS R01 HL113577NIH HHS R01 HL113577
6 · The paper itself

Abstract

In the neonatal respiratory distress syndrome (NRDS) and acute respiratory distress syndrome (ARDS), mechanical ventilation supports gas exchange but can cause ventilation-induced lung injury (VILI) that contributes to high mortality. Further, surface tension,

Indexed as

COVID-19Respiratory Distress SyndromeAnimalsHumansLungMaleRatsRespiration, ArtificialRhodaminesSARS-CoV-2Surface Tensionlissamine rhodamine BRhodaminesacute respiratory distress syndromeneonatal respiratory distress syndromeoxygenationsurface tensionventilation-induced lung injury

Identifiers

PMID33211596
PMCPMC8354824
OpenAlexW3103021285

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.