Evidence map›Paper›PMID 33211184›Full record

ArticlePediatric radiology2021

The Haskins pediatric atlas: a magnetic-resonance-imaging-based pediatric template and atlas.

Peter J Molfese, Daniel Glen, Laura Mesite, Robert W Cox, Fumiko Hoeft, Stephen J Frost, W Einar Mencl, Kenneth R Pugh, Peter A Bandettini

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Pediatric radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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  3. Processing, evaluating, and understanding FMRI data with afni_proc.py.Imaging neuroscience (Cambridge, Mass.) · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Peter J MolfeseHaskins Laboratories, 300 George St., Suite 900, New Haven, CT, 06511, USA. peter.molfese@nih.gov.ORCID 0000-0002-3045-9408
Daniel GlenScientific and Statistical Computing Core, National Institutes of Mental Health, National Institutes of Health, Bethesda, MD, USA.
Laura MesiteHaskins Laboratories, 300 George St., Suite 900, New Haven, CT, 06511, USA.
Robert W CoxScientific and Statistical Computing Core, National Institutes of Mental Health, National Institutes of Health, Bethesda, MD, USA.
Fumiko HoeftHaskins Laboratories, 300 George St., Suite 900, New Haven, CT, 06511, USA.
Stephen J FrostHaskins Laboratories, 300 George St., Suite 900, New Haven, CT, 06511, USA.
W Einar MenclHaskins Laboratories, 300 George St., Suite 900, New Haven, CT, 06511, USA.
Kenneth R PughHaskins Laboratories, 300 George St., Suite 900, New Haven, CT, 06511, USA.
Peter A BandettiniSection on Functional Imaging Methods, National Institutes of Mental Health, National Institutes of Health, Bethesda, MD, USA.
Haskins Laboratories · USNational Institutes of Health · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Functional MRI Method DevelopmentZIAMH002783 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI BANDETTINI, PETER · 2009 to 2025
$38.4M
Scientific and Statistical Computing CoreZICMH002888 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI TAYLOR, PAUL · 2009 to 2025
$30.9M
Visual word identification: phonology &morphologyP01HD001994 · NICHD · HASKINS LABORATORIES, INC. · PI MENCL, EINAR · 1985 to 2016
$23.5M
Tracking neurocognitive changes during evidence-based reading instruction in typically and atypically developing childrenR37HD090153 · NICHD · UNIVERSITY OF CONNECTICUT STORRS · PI Kenneth R. Pugh · 2017 to 2026
$6.0M
Understanding Obesity In Relation to the Built EnvironmentP20MD006899 · NIMHD · JACKSON STATE UNIVERSITY · PI ANTOINE-LAVIGNE, DONNA A · 2012 to 2016
$5.3M
Neurobiological Foundations of reading (dis)abilityR01HD048830 · NICHD · YALE UNIVERSITY · PI PUGH, KENNETH R. · 2005 to 2010
$3.0M
Intramural NIH HHS Z99 MH999999Intramural NIH HHS ZIA MH002783NCATS NIH HHS UL1 TR001863NICHD NIH HHS P01 HD001994NICHD NIH HHS PO1 HD-01994NICHD NIH HHS R01 HD 048830NICHD NIH HHS R01 HD048830NICHD NIH HHS R37 HD090153NIMHD NIH HHS P20 MD006899NIMH NIH HHS 1ZIAMH002783
6 · The paper itself

Abstract

backgroundSpatial normalization plays an essential role in multi-subject MRI and functional MRI (fMRI) experiments by facilitating a common space in which group analyses are performed. Although many prominent adult templates are available, their use for pediatric data is problematic. Generalized templates for pediatric populations are limited or constructed using older methods that result in less ideal normalization.

objectiveThe Haskins pediatric templates and atlases aim to provide superior registration and more precise accuracy in labeling of anatomical and functional regions essential for all fMRI studies involving pediatric populations. MATERIALS AND

methodsThe Haskins pediatric templates and atlases were generated with nonlinear methods using structural MRI from 72 children (age range 7-14 years, median 10 years), allowing for a detailed template with corresponding parcellations of labeled atlas regions. The accuracy of these templates and atlases was assessed using multiple metrics of deformation distance and overlap.

resultsWhen comparing the deformation distances from normalizing pediatric data between this template and both the adult templates and other pediatric templates, we found significantly less deformation distance for the Haskins pediatric template (P<0.0001). Further, the correct atlas classification was higher using the Haskins pediatric template in 74% of regions (P<0.0001).

conclusionThe Haskins pediatric template results in more accurate correspondence across subjects because of lower deformation distances. This correspondence also provides better accuracy in atlas locations to benefit structural and functional imaging analyses of pediatric populations.

Indexed as

AdolescentAdultBenchmarkingBrainChildDiagnostic Tests, RoutineHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingAtlasBrainChildrenDevelopmentMagnetic resonance imagingSpatial transformation

Identifiers

PMID33211184
PMCPMC7981247
OpenAlexW3105641049

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.