Evidence map›Paper›PMID 33211180›Full record

ArticleActa diabetologica2021

Diabetes distress and peripheral neuropathy are associated with medication non-adherence in individuals with type 2 diabetes in primary care.

Zhi Peng Zhang, M Premikha, Miyang Luo, Kavita Venkataraman

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Article in Acta diabetologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Zhi Peng ZhangNational University Polyclinics, Singapore, Singapore.
M PremikhaMinistry of Health Holdings Pte Ltd, Singapore, Singapore.
Miyang LuoSaw Swee Hock School of Public Health, National University of Singapore, 10-03J, Level 10, Tahir Foundation Building (MD1), 12 Science Drive 2, Singapore, 117549, Singapore.
Kavita VenkataramanSaw Swee Hock School of Public Health, National University of Singapore, 10-03J, Level 10, Tahir Foundation Building (MD1), 12 Science Drive 2, Singapore, 117549, Singapore. ephkv@nus.edu.sg.ORCID http://orcid.org/0000-0002-3139-6998
National University of Singapore · SGMinistry of Health · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPsychosocial factors like diabetes distress and social support, as well as the presence of complications, affect an individual's self-management ability; however, their role in adherence behaviours is not yet clear. We examined the role of psychosocial factors and complications in non-adherence behaviours in individuals with diabetes in primary care.

methodsBaseline survey with nine-month follow up through medical records of patients with type 2 diabetes attending primary care. Medication adherence and diabetes distress were assessed using Morisky Green Levine Medication Adherence Scale and Problem Areas in Diabetes, respectively. Appointment adherence was assessed through medical records.

resultsOf the 448 participants studied, 59.8% had medication non-adherence and 21.7% were non-adherent to scheduled appointments. PAID score (odds ratio (OR) 1.01, 95% confidence interval 1.00-1.03, p = 0.013), peripheral neuropathy (OR 1.99, 95%CI 1.18-3.37, p = 0.01), home glucose monitoring (OR 0.46, 95%CI 0.30-0.69, p < 0.001), HbA1c (OR 1.34, 95%CI 1.13-1.61, p = 0.001), and age (OR 0.96, 95%CI 0.93-0.98, p = 0.001) were associated with medication non-adherence. Indian ethnicity (OR 2.93, 95%CI 1.59-5.39, p = 0.001), secondary or higher education (OR 1.94, 95%CI 1.14-3.27, p = 0.014), and HbA1c (OR 1.38, 95%CI 1.18-1.63, p < 0.001) were associated with appointment non-adherence.

conclusionsNon-adherence behaviours were prevalent and significantly associated with higher HbA1c. Medication non-adherence was more likely in younger individuals, those with higher diabetes distress or peripheral neuropathy. Appointment non-adherence was more likely in individuals of Indian ethnicity or those with higher education. Greater support for these groups may help improve adherence behaviours and outcomes.

Indexed as

Drug MonitoringPsychological DistressAgedCross-Sectional StudiesDiabetes Mellitus, Type 2Diabetic NeuropathiesFemaleFollow-Up StudiesHumansHypoglycemic AgentsMaleMedication AdherenceMiddle AgedPeripheral Nervous System DiseasesPrimary Health CareSingaporeHypoglycemic AgentsAppointmentsComplicationsMedicationsNon-adherencePrimary carePsychosocial factorsType 2 diabetes mellitus

Identifiers

PMID33211180
OpenAlexW3104476003

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.