Evidence map›Paper›PMID 33211141›Full record

ArticleEuropean radiology2021

Static

Shuangshuang Song, Leiming Wang, Hongwei Yang, Yongzhi Shan, Ye Cheng, Lixin Xu, Chengyan Dong, Guoguang Zhao, Jie Lu

Abstract read
PubMed Publisher
In one paragraph

Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Assessment of Brain Tumour Perfusion Using Early-PhaseMolecular imaging and biology · 2024
    Article
  14. [European journal of nuclear medicine and molecular imaging · 2024
    Article
  15. Article
  16. Article
  17. Prediction of Glioma Grade and IDH Status UsingDiagnostics (Basel, Switzerland) · 2023
    Article
  18. Review
  19. Advanced MR Techniques for Preoperative Glioma Characterization: Part 2.Journal of magnetic resonance imaging : JMRI · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Shuangshuang SongDepartment of Radiology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Leiming WangDepartment of Pathology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Hongwei YangDepartment of Nuclear Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China.
Yongzhi ShanDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Ye ChengDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Lixin XuDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Chengyan DongGE Healthcare, Beijing, China.
Guoguang ZhaoDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Jie LuDepartment of Radiology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing, 100053, China. imaginglu@hotmail.com.ORCID http://orcid.org/0000-0003-0425-3921
Capital Medical University · CN

Funding

Beijing Higher Education Young Elite Teacher Project (CN) CIT&TCD201904091Beijing Municipal Administration of Hospitals' Ascent Plan DFL20180802
6 · The paper itself

Abstract

objectivesTo investigate the predictive value of static O-(2-

methodsFifty-two patients with newly diagnosed gliomas who underwent simultaneous

resultsTBRmean, TBRmax, nCBVmean, and nCBVmax differed between low- and high-grade gliomas, with the highest AUC of nCBVmean (0.920). TBRmax and nCBVmean showed significant differences between gliomas with and without IDH mutation (p = 0.032 and 0.010, respectively). Furthermore, TBRmean, TBRmax, and nCBVmean discriminated between IDH-wildtype glioblastomas and IDH-mutated astrocytomas (p = 0.049, 0.034 and 0.029, respectively). The combination of TBRmax and nCBVmean showed the best predictive performance (AUC, 0.903). Only nCBVmean differentiated IDH-mutated with 1p/19q codeletion oligodendrogliomas from IDH-wildtype glioblastomas (p < 0.001) (AUC, 0.829), but none of the parameters discriminated between oligodendrogliomas and astrocytomas.

conclusionsBoth FET PET and DSC-PWI might be non-invasive predictors for glioma grades and IDH mutation status. FET PET combined with CBV could improve the differentiation of IDH-mutated astrocytomas and IDH-wildtype glioblastomas. However, FET PET and CBV might be limited for identifying oligodendrogliomas. KEY POINTS: • Static

Indexed as

Brain NeoplasmsGliomaHumansIsocitrate DehydrogenaseMagnetic Resonance ImagingMutationNeoplasm GradingPositron-Emission TomographyRetrospective StudiesIsocitrate DehydrogenaseGliomaIsocitrate dehydrogenaseMolecular typingPerfusion magnetic resonance imagingPositron emission tomography

Identifiers

PMID33211141
OpenAlexW3105309972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.