Evidence map›Paper›PMID 33211135›Full record

ArticleIntensive care medicine2021

Clinical characteristics and day-90 outcomes of 4244 critically ill adults with COVID-19: a prospective cohort study.

COVID-ICU Group on behalf of the REVA Network and the COVID-ICU Investigators

5 registry-linked trialsAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Intensive care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 489 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
489citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04725084 completednot on this map

Comparison of Non-invasive Oxygenation Strategies in ICU Patients Admitted for Covid-19 Acute Respiratory Distress Syndrome

TypeobservationalSponsorCentre Hospitalier Intercommunal de Toulon La Seyne sur MerRan2020 to 2020Enrolled355ConditionsSevere Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)ArmsUse of High Flow Nasal Cannula alone, Use of Non-invasive Ventilation, Use of Continuous Positive Airway Pressure
NCT04840940 unknown statusnot on this map

Presepsin as an Early Biomarker for Ventilator-associated Pneumonia (VAP) Diagnosis in COVID-19 Patients: a Prospective Double Blind Observational Study

TypeobservationalSponsorSan Luigi Gonzaga HospitalRan2020 to 2021Enrolled50ConditionsVentilator Associated Pneumonia, Covid19
NCT04987528 active not recruitingnot on this map

Incidence, Risk Factors and Prognosis of Pulmonary Fibrosis During Severe COVID-19 Pneumonia

TypeobservationalSponsorHôpital Européen MarseilleRan2020 to 2027Enrolled200ConditionsSevere Acute Respiratory Syndrome Coronavirus 2, Acute Respiratory Distress Syndrome, Pulmonary FibrosisArmsAminoterminal type III peptide of procollagen, Lung computed tomography
NCT05392010 unknown statusnot on this mapstarted 2022, after this paper: background citation

Assessment of Clinical Practice of Mechanical Ventilation After COVID-19 Pan-demic Among 57 Countries: A Systematic Analysis for the Global BurdEn of Me-chanIcal VeNtilatIon (GEMINI Study) 2022, From VENTILAGROUP.

Typeobservational_patient_registrySponsorHospital Universitario GetafeRan2022 to 2024Enrolled10,900ConditionsMechanical Ventilation, Usual Care, Noninvasive Positive Pressure Ventilation, High Flow Oxygen TherapyArmsno intervention
NCT07510776 recruitingnot on this mapstarted 2025, after this paper: background citation

UP STUDY - Decipher Persistent Critical Illness Through in Deep Clinical Phenotyping.

TypeobservationalSponsorLisbon Academic Medical Center - Centro Académico de Medicina de LisboaRan2025 to 2027Enrolled7,000ConditionsCritical Illness, Recovery Outcomes, Critical Care, Intensive Care, Critical Care
3 · Its place in the literature

Who cites it

489 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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  11. Recent Advance Analysis of Recovery in Hospitalized People with COVID-19: A Systematic Review.International journal of environmental research and public health · 2022
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429 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

COVID-ICU Group on behalf of the REVA Network and the COVID-ICU Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe acute respiratory distress syndrome (ARDS) severity, ventilation management, and the outcomes of ICU patients with laboratory-confirmed COVID-19 and to determine risk factors of 90-day mortality post-ICU admission.

methodsCOVID-ICU is a multi-center, prospective cohort study conducted in 138 hospitals in France, Belgium, and Switzerland. Demographic, clinical, respiratory support, adjunctive interventions, ICU length-of-stay, and survival data were collected.

resultsFrom February 25 to May 4, 2020, 4643 patients (median [IQR] age 63 [54-71] years and SAPS II 37 [28-50]) were admitted in ICU, with day-90 post-ICU admission status available for 4244. On ICU admission, standard oxygen therapy, high-flow oxygen, and non-invasive ventilation were applied to 29%, 19%, and 6% patients, respectively. 2635 (63%) patients were intubated during the first 24 h whereas overall 3376 (80%) received invasive mechanical ventilation (MV) at one point during their ICU stay. Median (IQR) positive end-expiratory and plateau pressures were 12 (10-14) cmH

conclusionAmong more than 4000 critically ill patients with COVID-19 admitted to our ICUs, 90-day mortality was 31% and decreased from 42 to 25% over the study period. Mortality was higher in older, diabetic, obese and severe ARDS patients.

Indexed as

AgedBelgiumCOVID-19Critical IllnessFemaleFranceHospital MortalityHumansIntensive Care UnitsKaplan-Meier EstimateMaleMiddle AgedPatient AcuityProspective StudiesRespiration, ArtificialRespiratory Distress SyndromeAcute respiratory distress syndromeCOVID-19Mechanical ventilationMortality risk factorOutcome

Identifiers

PMID33211135
PMCPMC7674575

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.