ArticleJournal of magnetic resonance imaging : JMRI2021
Detecting Task Functional MRI Activation Using the Multiband Multiecho (MBME) Echo-Planar Imaging (EPI) Sequence.
Article in Journal of magnetic resonance imaging : JMRI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Impact of multi-echo ICA modeling decisions on motor-task fMRI analysis.Aperture neuro · 2026Article
- Robust-tedana: An automated denoising pipeline for multi-echo fMRI data.bioRxiv : the preprint server for biology · 2025Article
- Comparing the effect of multi-gradient echo and multi-band fMRI during a semantic task.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Deep linear matrix approximate reconstruction with integrated BOLD signal denoising reveals reproducible hierarchical brain connectivity networks from multiband multi-echo fMRI.Frontiers in neuroscience · 2025Article
- Optimization and validation of multi-echo, multi-contrast SAGE acquisition in fMRI.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Simultaneous cortical, subcortical, and brainstem mapping of sensory activation.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Simultaneous cortical, subcortical, and brainstem mapping of sensory activation.bioRxiv : the preprint server for biology · 2024Article
- Denoising task-correlated head motion from motor-task fMRI data with multi-echo ICA.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Denoising task-correlated head motion from motor-task fMRI data with multi-echo ICA.bioRxiv : the preprint server for biology · 2023Article
- Review
- A Semantic Cognition Contribution to Mood and Anxiety Disorder Pathophysiology.Healthcare (Basel, Switzerland) · 2023Review
- A comparison of multiband and multiband multiecho gradient-echo EPI for task fMRI at 3 T.Human brain mapping · 2023Article
- Contribution of the multi-echo approach in accelerated functional magnetic resonance imaging multiband acquisition.Human brain mapping · 2022Article
- Using multiband multi-echo imaging to improve the robustness and repeatability of co-activation pattern analysis for dynamic functional connectivity.NeuroImage · 2021Article
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6 authors.
Funding
Abstract
backgroundBlood oxygen level-dependent (BOLD) functional MRI (fMRI) has been widely applied to detect brain activations. Recent advances in multiband (MB) and multiecho (ME) techniques have greatly improved fMRI methods. MB imaging improves temporal and/or spatial resolution, while ME imaging has been shown to improve BOLD sensitivity. This study aimed to evaluate the novel MBME echo planar imaging (EPI) sequence utilizing MB and ME simultaneously to determine if the MBME outperform the MB single echo (MBSE) sequence for task fMRI. PURPOSE: To compare the performance of MBME with MBSE in a task fMRI study. STUDY TYPE: Prospective. POPULATION: A total of 29 healthy volunteers aged 20-46 years (9 male, 20 female). FIELD STRENGTH/SEQUENCE: MBSE and MBME gradient-echo EPI sequences were applied at 3T. Additional T ASSESSMENT: A checkerboard visual task was presented during the functional MBSE and MBME scans. The MBME or MBSE signal was evaluated using the temporal signal-to-noise ratio (tSNR). Task activation was evaluated using the z-score, volume, sensitivity, and specificity. Test-retest metrics of task activation were examined with the Dice coefficient (DC) and intraclass correlation coefficient (ICC) on subjects with repeated scans. STATISTICAL TESTS: A linear mixed-effects model was used to compared MBME and MBSE activation at the voxel base. The paired t-test was used to compare tSNR, activation z-score, and volume, along with sensitivity, specificity, and DC between MBSE and MBME.
resultsWhile similar task activation was detected in the visual cortex, MBME showed higher activation volume and higher sensitivity compared with MBSE (P < 0.05). ICC was higher for MBME than MBSE, while there was a trend of differences in DC (P = 0.08). DATA
conclusionMBME resulted in higher task fMRI activation volume and sensitivity without losing specificity. Reliability was also higher for MBME scans compared with MBSE. LEVEL OF EVIDENCE: 1 TECHNICAL EFFICACY STAGE: 1.
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