Evidence map›Paper›PMID 33210456›Full record

ArticleMaternal & child nutrition2021

Breastfeeding and the origins of health: Interdisciplinary perspectives and priorities.

Meghan B Azad, Nathan C Nickel, Lars Bode, Meredith Brockway, Amy Brown, Christina Chambers, Camie Goldhammer, Katie Hinde, Michelle McGuire, Daniel Munblit and 6 more

Open access · goldAbstract read
In one paragraph

Article in Maternal & child nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Facilitators and barriers to establishing lactation among women with diabetes?Diabetic medicine : a journal of the British Diabetic Association · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Importance of human milk for infants in the clinical setting: Updates and mechanistic links.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2023
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 15 institutions in 4 countries.

Meghan B AzadDepartment of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID 0000-0002-5942-4444
Nathan C NickelDevelopmental Origins of Chronic Diseases in Children Network (DEVOTION), Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada.ORCID 0000-0001-5836-5297
Lars BodeDepartment of Pediatrics and Larsson-Rosenquist Foundation Mother-Milk-Infant Center of Research Excellence, University of California San Diego, La Jolla, California, USA.
Meredith BrockwayDepartment of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada.
Amy BrownDepartment of Public Health, Policy and Social Sciences and Centre for Lactation, Infant Feeding and Translation, Swansea University, Swansea, UK.ORCID 0000-0002-0438-0157
Christina ChambersMommy's Milk Human Milk Research Biorepository, Center for Better Beginnings, University of California San Diego, San Diego, California, USA.
Camie GoldhammerIndigenous Breastfeeding Counsellor, Seattle, Washington, USA.
Katie HindeCenter of Evolution and Medicine and School of Human Evolution and Social Change, Arizona State University, Tempe, Arizona, USA.
Michelle McGuireMargaret Ritchie School of Family and Consumer Sciences, University of Idaho, Moscow, Idaho, USA.
Daniel MunblitDepartment of Paediatrics and Paediatric Infectious Diseases, Institute of Child's Health, Sechenov First Moscow State Medical University, Moscow, Russia.
Aloka L PatelDepartment of Pediatrics, Section of Neonatology, Rush University Children's Hospital, Chicago, Illinois, USA.
Rafael Pérez-EscamillaDepartment of Social and Behavioral Sciences, Yale School of Public Health, Yale University, New Haven, Connecticut, USA.ORCID 0000-0001-9416-8039
Kathleen M RasmussenDivision of Nutritional Sciences, Cornell University, Ithaca, New York, USA.
Natalie ShenkerDepartment of Surgery and Cancer, Imperial College London, London, UK.ORCID 0000-0002-8067-1079
Bridget E YoungDivision of Allergy and Immunology, Department of Pediatrics, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA.
Luisa ZuccoloMRC Integrative Epidemiology Unit and Department of Population Health Sciences, University of Bristol, Bristol, UK.
Research Manitoba · CAArizona State University · USCornell University · USImperial College London · GBManitoba Health · CAMothers’ Milk Bank · USRush Children's Hospital · USSeattle Reproductive Medicine · USSechenov University · RUSwansea University · GBUniversity of Bristol · GBUniversity of California San Diego · USUniversity of Idaho · USUniversity of Rochester · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Medical Research Council MR/S017437/1NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Breastfeeding and human milk (HM) are critically important to maternal, infant and population health. This paper summarizes the proceedings of a workshop that convened a multidisciplinary panel of researchers to identify key priorities and anticipated breakthroughs in breastfeeding and HM research, discuss perceived barriers and challenges to achieving these breakthroughs and propose a constructive action plan to maximize the impact of future research in this field. Priority research areas identified were as follows: (1) addressing low breastfeeding rates and inequities using mixed methods, community partnerships and implementation science approaches; (2) improving awareness of evidence-based benefits, challenges and complexities of breastfeeding and HM among health practitioners and the public; (3) identifying differential impacts of alternative modes of HM feeding including expressed/pumped milk, donor milk and shared milk; and (4) developing a mechanistic understanding of the health effects of breastfeeding and the contributors to HM composition and variability. Key barriers and challenges included (1) overcoming methodological limitations of epidemiological breastfeeding research and mechanistic HM research; (2) counteracting 'breastfeeding denialism' arising from negative personal breastfeeding experiences; (3) distinguishing and aligning research and advocacy efforts; and (4) managing real and perceived conflicts of interest. To advance research on breastfeeding and HM and maximize the reach and impact of this research, larger investments are needed, interdisciplinary collaboration is essential, and the scientific community must engage families and other stakeholders in research planning and knowledge translation.

Indexed as

Breast FeedingMilk, HumanFemaleHumansInfantbreastfeedingbreastmilkconflict of interesthuman milkinfant feedinglactationresearch methodology

Identifiers

PMID33210456
PMCPMC7988860
OpenAlexW3106040203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.