ArticleInfancy : the official journal of the International Society on Infant Studies2021
Cognitive function in toddlers with congenital heart disease: The impact of a stimulating home environment.
Article in Infancy : the official journal of the International Society on Infant Studies, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 43 citations in OpenAlex.
- Sociodemographic Characteristics and Behavioral Outcomes in Infants With Hypoxic-Ischemic Encephalopathy Treated With Therapeutic Hypothermia.Pediatric neurology · 2025Trial
- Neonatal brain structure, cognitively stimulating parenting and behavioural outcomes in preschool children with congenital heart disease and controls.Scientific reports · 2026Article
- A machine learning classifier to identify and prioritise genes associated with murine cardiac development.PLoS genetics · 2026Article
- Psychomotor Development in Pediatric Patients with Congenital Heart Defects Prior to Surgical Intervention: Findings from a Prospective Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2026Article
- Behavioral outcomes of preschool children with congenital heart disease and controls.Frontiers in pediatrics · 2026Article
- Rethinking cardiac neurodevelopment: a dimensional model of adversity in congenital heart disease.Frontiers in pediatrics · 2026Article
- Cognitive disengagement syndrome and peer relationships of youth with critical congenital heart defects.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2025Article
- The role of social determinants of health in the developing injured brain.Current opinion in pediatrics · 2025Review
- Effect of Fetal Brain Oxygenation and Volume on Brain Maturation and Neurodevelopmental Outcomes in Congenital Heart Disease.Radiology · 2025Article
- Radiomics models predict early neurodevelopment in infants with congenital cardiac septal defects.Quantitative imaging in medicine and surgery · 2025Article
- Fertility of Adults Born Very Preterm or With Very Low Birth Weight.JAMA network open · 2025Article
- School Readiness in Preschool-Age Children with Critical Congenital Heart Disease.Pediatric cardiology · 2025Article
- Assessment of Neurodevelopmental Outcomes in Children With Congenital Heart Disease Using Magnetic Resonance Imaging (MRI): Focus on Brain Volume as a Predictor of Neurodevelopmental Abnormalities.Journal of multidisciplinary healthcare · 2025Article
- The cumulative impact of clinical risk on brain networks and associations with executive function impairments in adolescents with congenital heart disease.Human brain mapping · 2024Article
- Postnatal Brain Trajectories and Maternal Intelligence Predict Childhood Outcomes in Complex CHD.Journal of clinical medicine · 2024Article
- Article
- Effect of play-based intervention on children's mental status and caregiver involvement during hospitalization: findings from Pakistan.BMC pediatrics · 2024Article
- Executive Function in Preschool Children with Congenital Heart Disease and Controls: The Role of a Cognitively Stimulating Home Environment.The Journal of pediatrics · 2024Article
- Predictors of the inability to achieve full oral feeding in postoperative infants with CHD.Cardiology in the young · 2024Article
- Neuroimaging and Neurodevelopmental Outcomes Among Individuals With Complex Congenital Heart Disease: JACC State-of-the-Art Review.Journal of the American College of Cardiology · 2023Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
Infants born with congenital heart disease (CHD) are at increased risk of neurodevelopmental difficulties in childhood. The extent to which perioperative factors, cardiac physiology, brain injury severity, socioeconomic status, and home environment influence early neurodevelopment is not clear. Sixty-nine newborns with CHD were recruited from St Thomas' Hospital. Infants underwent presurgical magnetic resonance imaging on a 3-Tesla scanner situated on the neonatal unit. At 22 months, children completed the Bayley Scales of Infant and Toddler Development-3rd edition and parents completed the cognitively stimulating parenting scale to assess cognitive stimulation at home. Level of maternal education and total annual household income were also collected. Hospital records were reviewed to calculate days on the intensive care unit post-surgery, time on bypass during surgery, and days to corrective or definitive palliative surgical intervention. In the final analysis of 56 infants, higher scores on the cognitively stimulating parenting scale were associated with higher cognitive scores at age 22 months, correcting for gestational age at birth, sex, and maternal education. There were no relationships between outcome scores and clinical factors; socioeconomic status; or brain injury severity. Supporting parents to provide a stimulating home environment for children may promote cognitive development in this high-risk population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.