Observational studyJournal of internal medicine2021
Estimated salt intake and risk of atrial fibrillation in a prospective community-based cohort.
Observational study in Journal of internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Pooled it
- Dietary interventions in the management of atrial fibrillation.Frontiers in cardiovascular medicine · 2024Pooled it
- Sodium Intake and Incident Atrial Fibrillation in Individuals With Vascular Disease.JAMA network open · 2024Trial
- Trends of Global Burden of Cardiovascular Diseases Attributable to High Sodium Intake From 1990 to 2021 and Projections to 2030: A Population-Based Study.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- Association of Adding Salt to Foods and Potassium Intake with Incident Atrial Fibrillation in the UK Biobank Study.Reviews in cardiovascular medicine · 2024Article
- Sex differences in association of healthy eating pattern with all-cause mortality and cardiovascular mortality.BMC public health · 2024Article
- Review
- P-wave peak time and P-wave dispersion in surface electrocardiography as initial predictors of new-onset atrial fibrillation in early-onset hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Excessive salt intake accelerates the progression of cerebral small vessel disease in older adults.BMC geriatrics · 2023Article
- The association between sodium intake and coronary and carotid atherosclerosis in the general Swedish population.European heart journal open · 2023Article
- Evaluating the association between dietary salt intake and the risk of atrial fibrillation using Mendelian randomization.Frontiers in nutrition · 2023Article
- Mediterranean Diet: A Tool to Break the Relationship of Atrial Fibrillation with the Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease.Nutrients · 2022Review
- Population-Level Analyses of Alcohol Consumption as a Predictor of Acute Atrial Fibrillation Episodes.Nature cardiovascular research · 2022Article
- Association of Sleep Patterns and Lifestyles With Incident Hypertension: Evidence From a Large Population-Based Cohort Study.Frontiers in cardiovascular medicine · 2022Article
- Estimated salt intake and risk of atrial fibrillation in a prospective community-based cohort.Journal of internal medicine · 2021Observational
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
Abstract
introductionHypertension predisposes to atrial fibrillation (AF) - a major risk factor for ischaemic stroke. Since a high dietary salt consumption is associated with hypertension, we investigated the association between urinary sodium excretion as a marker for dietary sodium intake and risk of new-onset AF in community-dwelling adults.
methodThe UK Biobank includes 40- to 69-year-old British residents recruited 2006-2010. Participants were divided into sex-specific quintiles according to 24-hour sodium excretion estimated based on spot samples with the Kawasaki equation. We excluded participants with AF at baseline. Cox regression adjusted for cardiovascular risk factors was used to assess associations with risk of AF, using the third quintile as reference.
resultsA total of 257 545 women and 215 535 men were included. During up to 10 years' follow-up, 2221 women and 3751 men were diagnosed with AF. There was a tendency for an increased risk of AF in the lowest and highest quintiles of estimated daily salt intake in both women and men. In the fully adjusted model, significant associations were seen amongst men in the lowest and highest quintiles of sodium excretion (hazard ratio, HR
conclusionWe found evidence for a U-shaped association between estimated daily salt intake and AF risk amongst men. A suggestive J-shaped association in women was not statistically confirmed, but analyses were likely underpowered. Our results suggest that above a certain physiological minimum level progressively higher salt intake is associated with increasing risk of AF.
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