Evidence map›Paper›PMID 33210370›Full record

ArticleThe Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association2022

Exceptional Survival Among Kentucky Stage IV Non-small Cell Lung Cancer Patients: Appalachian Versus Non-Appalachian Populations.

Vira Pravosud, Nathan L Vanderford, Bin Huang, Thomas C Tucker, Susanne M Arnold

Open access · greenAbstract read
In one paragraph

Article in The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Vira PravosudDepartment of Epidemiology, College of Public Health, University of Kentucky, Lexington, Kentucky.ORCID 0000-0002-5762-6632
Nathan L VanderfordDepartment of Toxicology and Cancer Biology, College of Medicine, University of Kentucky, Lexington, Kentucky.
Bin HuangDivision of Cancer Biostatistics, Department of Internal Medicine, College of Medicine, University of Kentucky, Lexington, Kentucky.
Thomas C TuckerDepartment of Epidemiology, College of Public Health, University of Kentucky, Lexington, Kentucky.
Susanne M ArnoldDivision of Medical Oncology, Department of Internal Medicine, College of Medicine, University of Kentucky, Lexington, Kentucky.
University of Kentucky · US

Funding

University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI KATHLEEN L. O'CONNOR · 2013 to 2026
$38.3M
University of Kentucky Center for Cancer MetabolismP20GM121327 · NIGMS · UNIVERSITY OF KENTUCKY · PI Binhua P Zhou · 2017 to 2026
$25.0M
Appalachian Career Training in Oncology (ACTION) ProgramR25CA221765 · NCI · UNIVERSITY OF KENTUCKY · PI Nathan Lane Vanderford · 2018 to 2026
$3.7M
NCI NIH HHS P30 CA177558NCI NIH HHS R25 CA221765NIGMS NIH HHS P20 GM121327
6 · The paper itself

Abstract

purposeTo determine differences in exceptional survival (ES)-survival of 5 years or more past diagnosis-between stage IV non-small cell lung cancer (NSCLC) patients residing in the Appalachian versus non-Appalachian regions of Kentucky.

methodsThis was a population-based, retrospective case-control study of Kentucky patients, diagnosed with stage IV NSCLC between January 1, 2000, and December 31, 2011. The data were drawn from the Kentucky Cancer Registry.

findingsFindings from the multivariable logistic regression revealed no significant differences in the odds of ES between patients who resided in Appalachian versus non-Appalachian Kentucky. Being female and undergoing surgery only as the first course of treatment were associated with higher odds of ES. Increasing age, unspecified histology, having poorly differentiated or undifferentiated carcinomas, and receiving radiation therapy only as the first course of treatment were associated with decreased odds of ES.

conclusionDifferences in the odds of ES among stage IV NSCLC patients were not related to residence in Appalachian versus non-Appalachian Kentucky. ES was associated with other nongenetic and treatment factors that warrant further investigations.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsAppalachian RegionCase-Control StudiesFemaleHumansKentuckyRetrospective StudiesAppalachiaCharlson comorbidity index (CCI)exceptional survivalruralstage IV non-small cell lung cancer (NSCLC)

Identifiers

PMID33210370
PMCPMC9106424
OpenAlexW3099427697

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.