Evidence map›Paper›PMID 33210243›Full record

ArticleProtein & cell2021

Repurposing FDA-approved drugs for SARS-CoV-2 through an ELISA-based screening for the inhibition of RBD/ACE2 interaction.

Wenyu Fu, Yujianan Chen, Kaidi Wang, Aubryanna Hettinghouse, Wenhuo Hu, Jing-Quan Wang, Zi-Ning Lei, Zhe-Sheng Chen, Kenneth A Stapleford, Chuan-Ju Liu

Open access · diamondAbstract readLetterComment
In one paragraph

Article in Protein & cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
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  3. A Natural Bioactive Peptide fromInternational journal of molecular sciences · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Wenyu Fu *Department of Orthopaedic Surgery, New York University Medical Center, 301 East 17th Street, New York, NY, 10003, USA.
Yujianan Chen *Department of Orthopaedic Surgery, New York University Medical Center, 301 East 17th Street, New York, NY, 10003, USA.
Kaidi Wang *Department of Orthopaedic Surgery, New York University Medical Center, 301 East 17th Street, New York, NY, 10003, USA.
Aubryanna HettinghouseDepartment of Orthopaedic Surgery, New York University Medical Center, 301 East 17th Street, New York, NY, 10003, USA.
Wenhuo HuHuman Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
Jing-Quan WangDepartment of Pharmaceutical Science, College of Pharmacy and Health Sciences, St. John's University, New York, NY, 11439, USA.
Zi-Ning LeiDepartment of Pharmaceutical Science, College of Pharmacy and Health Sciences, St. John's University, New York, NY, 11439, USA.
Zhe-Sheng ChenDepartment of Pharmaceutical Science, College of Pharmacy and Health Sciences, St. John's University, New York, NY, 11439, USA.
Kenneth A StaplefordDepartment of Microbiology, New York University School of Medicine, New York, NY, 10016, USA. Kenneth.Stapleford@nyulangone.org.ORCID 0000-0002-7796-2254
Chuan-Ju LiuDepartment of Orthopaedic Surgery, New York University Medical Center, 301 East 17th Street, New York, NY, 10003, USA. chuanju.liu@nyumc.org.ORCID 0000-0002-7181-8032
Columbia University Irving Medical Center · USSt. John's University · USMemorial Sloan Kettering Cancer Center · USNew York University · US

Funding

The immunological mechanism of PGRNs anti-inflammatory effect - Renewal - 1R01AR062207 · NIAMS · YALE UNIVERSITY · PI Chuanju Liu · 2012 to 2026
$5.6M
The Role of PGRN Growth Factor in Osteoarthritis. - Renewal - 1 - Revision - 2R01AR061484 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI LIU, CHUANJU · 2011 to 2020
$4.8M
Progranulin: A Novel Gene in Gaucher DiseasesR01NS103931 · NINDS · YALE UNIVERSITY · PI Chuanju Liu, Ying Sun · 2017 to 2026
$4.3M
Targeting TNF Receptors to Inhibit Inflammation and to Prompt Bone Regeneration in Type 1 Diabetes - Resubmission - 1R01AR076900 · NIAMS · YALE UNIVERSITY · PI LIU, CHUANJU · 2020 to 2024
$2.0M
NIAMS NIH HHS R01 AR061484NIAMS NIH HHS R01 AR062207NIAMS NIH HHS R01 AR076900NINDS NIH HHS R01 NS103931
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19Pharmaceutical PreparationsAngiotensin-Converting Enzyme 2Drug RepositioningEnzyme-Linked Immunosorbent AssayHumansSARS-CoV-2Angiotensin-Converting Enzyme 2Pharmaceutical Preparations

Identifiers

PMID33210243
PMCPMC7673315
OpenAlexW3105880285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.