Evidence map›Paper›PMID 33210207›Full record

ArticleIndian journal of pediatrics2021

Acute Kidney Injury in Pediatric Diabetic Ketoacidosis.

Eun Mi Yang, Hyun Gyung Lee, Ka Young Oh, Chan Jong Kim

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In one paragraph

Article in Indian journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05508490 (Prevalence of Acute Kidney Injury in Patients With Diabetic Ketoacidosis), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05508490 unknown statusnot on this mapstarted 2023, after this paper: background citation

Prevalence of Acute Kidney Injury in Patients With Diabetic Ketoacidosis

TypeobservationalSponsorAssiut UniversityRan2023 to 2024Enrolled100ConditionsAKI in Diabetic KetoacidosisArmsrenal chemistry, serum electrolyte,
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Eun Mi YangDepartment of Pediatrics, Chonnam National University Hospital and Medical School, Gwangju, South Korea.ORCID https://orcid.org/0000-0001-9410-5855
Hyun Gyung LeeDepartment of Pediatrics, Chonnam National University Hospital and Medical School, Gwangju, South Korea.ORCID https://orcid.org/0000-0001-9131-9700
Ka Young OhDepartment of Pediatrics, Jeil Hospital, Yeosu, South Korea.ORCID https://orcid.org/0000-0002-8054-4520
Chan Jong KimDepartment of Pediatrics, Chonnam National University Hospital and Medical School, Gwangju, South Korea. cjkim@jnu.com.ORCID https://orcid.org/0000-0001-6519-2427
Chonnam National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the incidence and clinical characteristics of acute kidney injury (AKI) and identify the associated risk factors for AKI in children with type 1 diabetes mellitus (T1DM) and diabetic ketoacidosis (DKA).

methodsThis was a retrospective study performed over 15 y in a single Korean center. Children aged ≤18-y-old with T1DM and DKA were enrolled and divided into 2 groups according to the presence of AKI.

resultsThis study included 90 episodes of DKA in 58 children with T1DM. AKI occurred in a total of 70 hospitalizations (77.8%) of 44 children: 18 (20.0%) with stage 1 AKI, 39 (43.3%) with stage 2 AKI, and 13 (14.4%) with stage 3 AKI. The number of AKI decreased to 28 (47.4%) and 13 (28.3%) after 12 h and 24 h of admission, respectively. The white blood cell count (P = 0.001) and anion gap levels (P = 0.025) were significantly higher and serum bicarbonate level (P = 0.004) was lower in the AKI group. Logistic regression analysis revealed that a longer duration of TIDM and high anion gap were independent predictors of developing severe AKI in pediatric DKA with T1DM (odds ratio, 1.225, P = 0.013; odds ratio, 1.130, P = 0.038).

conclusionsAKI frequently occurred in TIDM children with DKA. Longer duration of TIDM and elevated anion gap are associated with occurrence of severe AKI.

Indexed as

Acute Kidney InjuryDiabetes Mellitus, Type 1Diabetic KetoacidosisAgedChildHumansIncidenceRetrospective StudiesAcute kidney injuryChildrenDiabetes mellitusDiabetic ketoacidosis

Identifiers

PMID33210207
OpenAlexW3101961735

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.