ArticleJAC-antimicrobial resistance2020
Factors influencing choices of empirical antibiotic treatment for bacterial infections in a scenario-based survey in Vietnam.
Article in JAC-antimicrobial resistance, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 17 citations in OpenAlex.
- Role of diagnostic testing in reducing unnecessary antibiotic use for upper respiratory tract infections in Chinese primary healthcare: a mixed-methods study.BMC primary care · 2026Article
- Compliance with the national and WHO antibiotic treatment guidelines for respiratory tract infections and their association with clinical and economic outcomes in Vietnam: an observational study.JAC-antimicrobial resistance · 2025Article
- Clinicians' interpretation of thresholds in hospital antibiograms for gram-negative rod infections: A survey and contingent valuation study of hospitalists.Journal of hospital medicine · 2024Article
- Antibiotic prescribing practices of medical doctors in a resource-limited setting and the influence of individual perceptions and stewardship support: a survey in three tertiary hospitals in Vietnam.JAC-antimicrobial resistance · 2024Article
- Review of antibiotic prescriptions as part of antimicrobial stewardship programmes: results from a pilot implementation at two provincial-level hospitals in Viet Nam.JAC-antimicrobial resistance · 2023Article
- Prevalence and characteristics of antibiotic prescription for acute COVID-19 patients in Japan.Scientific reports · 2022Article
- Changing Patterns of Causative Pathogens over Time and Efficacy of Empirical Antibiotic Therapies in Acute Cholangitis with Bacteremia.Gut and liver · 2022Article
- Investigation of factors influencing inpatient antibiotic prescribing decisions in the Veterans' Health Administration.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2022Article
- Antibiotic use for empirical therapy in the critical care units in primary and secondary hospitals in Vietnam: a multicenter cross-sectional study.The Lancet regional health. Western Pacific · 2022Article
- Interplay between Phenotypic Resistance to Relevant Antibiotics in Gram-Negative Urinary Pathogens: A Data-Driven Analysis of 10 Years' Worth of Antibiogram Data.Life (Basel, Switzerland) · 2021Article
- Appropriate Antibiotic Use and Associated Factors in Vietnamese Outpatients.Healthcare (Basel, Switzerland) · 2021Article
- Strategies to Improve Antimicrobial Utilization with a Special Focus on Developing Countries.Life (Basel, Switzerland) · 2021Review
- Improving antibiotic prescribing for community-acquired pneumonia in a provincial hospital in Northern Vietnam.JAC-antimicrobial resistance · 2021Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundAntimicrobial stewardship (AMS) programmes have been implemented around the world to guide rational use of antibiotics but implementation is challenging, particularly in low- and middle-income countries, including Vietnam. Understanding factors influencing doctors' prescribing choices for empirical treatment can help design AMS interventions in these settings.
objectivesTo understand doctors' choices of antibiotics for empirical treatment of common bacterial infections and the factors influencing decision-making.
methodsWe conducted a cross-sectional survey among medical professionals applying for a postgraduate programme at Hanoi Medical University, Vietnam. We used a published survey developed for internal medicine doctors in Canada. The survey was self-administered and included four clinical scenarios: (i) severe undifferentiated sepsis; (ii) mild undifferentiated sepsis; (iii) severe genitourinary infection; and (iv) mild genitourinary infection.
resultsA total of 1011/1280 (79%), 683/1188 (57.5%), 718/1157 (62.1%) and 542/1062 (51.0%) of the participants selected combination therapy for empirical treatment in scenarios 1, 2, 3 and 4, respectively. Undifferentiated sepsis (OR 1.82, 95% CI 1.46-2.27 and 2.18, 1.51-3.16 compared with genitourinary) and severe infection (1.33, 1.24-1.43 and 1.38, 1.21-1.58 compared with mild) increased the likelihood of choosing a combination therapy and a carbapenem regimen, respectively. Participants with higher acceptable minimum threshold for treatment coverage and young age were also more likely to prescribe carbapenems.
conclusionsDecision-making in antibiotic prescribing among doctors in Vietnam is influenced by both disease-related characteristics and individual factors, including acceptable minimum treatment coverage. These findings are useful for tailoring AMS implementation in Vietnam and other, similar settings.
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What OpenQuestion holds
Registered trials
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