Evidence map›Paper›PMID 33210068›Full record

ArticleJBMR plus2020

Impact of Type 1 Diabetes Mellitus on Skeletal Integrity and Strength in Adolescents as Assessed by HRpQCT.

Janani Devaraja, Richard Jacques, Margaret Paggiosi, Carolyn Clark, Paul Dimitri

Open access · goldAbstract read
In one paragraph

Article in JBMR plus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Contributions of Bone Microarchitecture to Skeletal Fragility in Adults with Longstanding Type 1 Diabetes.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026
    Article
  4. Bone microstructure and TBS in diabetes: what have we learned? A narrative review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Review
  5. Article
  6. Article
  7. Assessment of fracture risk in diabetic patients.Journal of diabetes and metabolic disorders · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Bone Microarchitecture and Strength in Long-Standing Type 1 Diabetes.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2022
    Article
  14. Review
  15. Review
  16. The Role of Irisin in Exercise-Mediated Bone Health.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Janani DevarajaDepartment of Paediatric Endocrinology Sheffield Children's NHS Foundation Trust Sheffield UK.
Richard JacquesThe School of Health and Related Research, University of Sheffield Sheffield UK.ORCID https://orcid.org/0000-0001-6710-5403
Margaret PaggiosiMellanby Centre for Bone Research University of Sheffield Sheffield UK.ORCID https://orcid.org/0000-0002-1030-0723
Carolyn ClarkDirectorate of Research & Innovation, Sheffield Children's NHS Foundation Trust Sheffield UK.
Paul DimitriDepartment of Paediatric Endocrinology Sheffield Children's NHS Foundation Trust Sheffield UK.ORCID https://orcid.org/0000-0001-7625-6713
Sheffield Children's NHS Foundation Trust · GBUniversity of Sheffield · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adults with type 1 diabetes mellitus (T1DM) are at risk of premature osteoporosis and fractures. The onset of T1DM typically starts during childhood and adolescence. Thus, the effects of DM on the skeleton may be established during this period. Studies in children with T1DM primarily use DXA with conflicting results. We present the first study in adolescents assessing the impact of T1DM on skeletal microstructure and strength using HRpQCT. We recruited 22 patients aged 12 to 16 years with T1DM who were matched by age, gender, and pubertal stage with healthy controls. Paired

Indexed as

DXAFRACTURE RISK ASSESSMENTOTHERRADIOLOGY

Identifiers

PMID33210068
PMCPMC7657396
OpenAlexW3091985660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.