ArticleInfectious Disease Modelling2020
A co-interaction model of HIV and syphilis infection among gay, bisexual and other men who have sex with men.
Article in Infectious Disease Modelling, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 8 citations in OpenAlex.
- Prospects of HIV elimination among men who have sex with men: A systematic review of modeling studies.PLoS computational biology · 2026Pooled it
- Prevalence, incidence and risk factors of syphilis among men who have sex with men in China from 2013 to 2025: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Mechanistic Models of Virus-Bacteria Co-Infections in Humans: A Systematic Review of Methods and Assumptions.Pathogens (Basel, Switzerland) · 2025Pooled it
- Modelling assessment of epidemiological strategies based on self-screening tools.Communications medicine · 2026Article
- Successful Scale-up of Syphilis Testing Linked to Routine HIV Viral Load Monitoring in British Columbia.Open forum infectious diseases · 2026Article
- Identifying Subgroups of People Living With HIV in British Columbia, Canada Based on Sexually Transmitted and Blood-Borne Infection Testing and Diagnostic Laboratory Data: A Retrospective Cohort Study.Health science reports · 2026Article
- Rapid Plasma Reagin Tests of Serum, Cerebrospinal Fluid, and Aqueous Humor of Patients With Ocular Syphilis and AIDS.Journal of ophthalmology · 2026Article
- Impact of screening and doxycycline prevention on the syphilis epidemic among men who have sex with men in British Columbia: a mathematical modelling study.Lancet regional health. Americas · 2024Article
- Understanding HIV/AIDS dynamics: insights from CD4+T cells, antiretroviral treatment, and country-specific analysis.Frontiers in public health · 2024Article
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Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We developed a mathematical model to study the co-interaction of HIV and syphilis infection among gay, bisexual and other men who have sex with men (gbMSM). We qualitatively analysed the model and established necessary conditions under which disease-free and endemic equilibria are asymptotically stable. We gave analytical expressions for the reproduction number, and showed that whenever the reproduction numbers of sub-models and co-interaction model are less than unity, the epidemics die out, while epidemics persist when they are greater than unity. We presented numerical simulations of the full model and showed qualitative changes of the dynamics of the full model to changes in the transmission rates. Our numerical simulations using a set of reasonable parameter values showed that: (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.