Evidence map›Paper›PMID 33210021›Full record

ArticleBioactive materials2021

Microstructure evolution and texture tailoring of reduced graphene oxide reinforced Zn scaffold.

Youwen Yang, Yun Cheng, Shuping Peng, Liang Xu, Chongxian He, Fangwei Qi, Mingchun Zhao, Cijun Shuai

Open access · goldAbstract read
In one paragraph

Article in Bioactive materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 176 citations in OpenAlex.

  1. Article
  2. Bioactive materials · 2025
    Article
  3. Review
  4. Review
  5. Review
  6. Graphene in 3D Bioprinting.Journal of functional biomaterials · 2024
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Multifunctional Arabinoxylan-Frontiers in bioengineering and biotechnology · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Youwen YangInstitute of Bioadditive Manufacturing, Jiangxi University of Science and Technology, Nanchang, 330013, China.
Yun ChengInstitute of Bioadditive Manufacturing, Jiangxi University of Science and Technology, Nanchang, 330013, China.
Shuping PengNHC Key Laboratory of Carcinogenesis, School of Basic Medical Science, Central South University, Changsha, Hunan, 410013, China.
Liang XuSchool of Energy and Machinery Engineering, Jiangxi University of Science and Technology, Nanchang, 330013, China.
Chongxian HeInstitute of Bioadditive Manufacturing, Jiangxi University of Science and Technology, Nanchang, 330013, China.
Fangwei QiInstitute of Bioadditive Manufacturing, Jiangxi University of Science and Technology, Nanchang, 330013, China.
Mingchun ZhaoSchool of Materials and Engineering, Central South University, Changsha, 410083, China.
Cijun ShuaiInstitute of Bioadditive Manufacturing, Jiangxi University of Science and Technology, Nanchang, 330013, China.
Jiangxi University of Science and Technology · CNCentral South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zinc (Zn) possesses desirable degradability and favorable biocompatibility, thus being recognized as a promising bone implant material. Nevertheless, the insufficient mechanical performance limits its further clinical application. In this study, reduced graphene oxide (RGO) was used as reinforcement in Zn scaffold fabricated via laser additive manufacturing. Results showed that the homogeneously dispersed RGO simultaneously enhanced the strength and ductility of Zn scaffold. On one hand, the enhanced strength was ascribed to (i) the grain refinement caused by the pinning effect of RGO, (ii) the efficient load shift due to the huge specific surface area of RGO and the favorable interface bonding between RGO and Zn matrix, and (iii) the Orowan strengthening by the homogeneously distributed RGO. On the other hand, the improved ductility was owing to the RGO-induced random orientation of grain with texture index reducing from 20.5 to 7.3, which activated more slip systems and provided more space to accommodate dislocation. Furthermore, the cell test confirmed that RGO promoted cell growth and differentiation. This study demonstrated the great potential of RGO in tailoring the mechanical performance and cell behavior of Zn scaffold for bone repair.

Indexed as

Cell behaviorLaser additive manufacturingMechanical performanceRGOZn scaffold

Identifiers

PMID33210021
PMCPMC7653236
OpenAlexW3102500925

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.