ReviewBioactive materials2021
Biological applications of copper-containing materials.
Review in Bioactive materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 1 synthesis or guideline pooled it, 212 citations in OpenAlex.
- Toxic Metal in Plant-Based Therapeutics: Contamination Pathways, Oxidative Stress Induction, and Onset of Disease.TheScientificWorldJournal · 2026Pooled it
- Synthesis, characterization, and DNA binding of Ni(II), Cu(II), and Zn(II) complexes with a novel N,O-bidentate acylhydrazone.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026Article
- Plasmonics of non-noble metals.RSC advances · 2026Review
- Skin-mimetic bilayer hydrogel normalizes diabetic wound healing by orchestrating inflammatory cell dynamics: An early intervention strategy.Bioactive materials · 2026Article
- Potential Use of Grape Pomace for the Development of New Products: Study of Inorganic Elements Through Simulated Gastrointestinal Digestion.Foods (Basel, Switzerland) · 2026Article
- Copper Metabolism in Isolated Macrophages: Regulator of Immunity and Inflammation.Veterinary sciences · 2026Review
- Harnessing copper-strontium synergy in an injectable composite for multi-pathway bone regeneration.RSC advances · 2026Article
- Carbon Quantum Dot-Based Sensors: Photochemical Principles and Multimodal Applications.Materials (Basel, Switzerland) · 2026Review
- Structure-Driven Bioactivity of Chitosan-Agarose-Gelatin Hydrogels Functionalized with Tannic Acid-CuACS applied materials & interfaces · 2026Article
- Development of AuACS applied materials & interfaces · 2026Article
- Synthesis and CuPhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026Article
- High-ResolutionMolecules (Basel, Switzerland) · 2025Article
- Dual-responsive copper complex delivered by dissolvable microneedle promotes polymicrobial infection eradication and cutaneous wound healing.Materials today. Bio · 2025Article
- Characterization of the Binding Modes of CuInternational journal of molecular sciences · 2025Article
- Enhanced piezocatalytic therapy of MRSA-infected osteomyelitis using ultrasound-triggered copper nanocrystals-doped barium titanate.Bioactive materials · 2025Article
- Sustainable recovery of copper from wastewater via zinc cementation enhanced by natural chalcone-based accelerators.Scientific reports · 2025Article
- Association between serum Copper-Zinc-Selenium mixture and multiple health outcomes.Bioactive materials · 2025Article
- Review
- Food-Derived Micronutrients as Alleviators of Age-Related Dysfunction: A Dive into Their Effects and Cellular Mechanisms.Indian journal of clinical biochemistry : IJCB · 2025Review
- Recent advances in NIR-II photothermal and photodynamic therapies for drug-resistant wound infections.Materials today. Bio · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Copper is an indispensable trace metal element in the human body, which is mainly absorbed in the stomach and small intestine and excreted into the bile. Copper is an important component and catalytic agent of many enzymes and proteins in the body, so it can influence human health through multiple mechanisms. Based on the biological functions and benefits of copper, an increasing number of researchers in the field of biomaterials have focused on developing novel copper-containing biomaterials, which exhibit unique properties in protecting the cardiovascular system, promoting bone fracture healing, and exerting antibacterial effects. Copper can also be used in promoting incisional wounds healing, killing cancer cells, Positron Emission Tomography (PET) imaging, radioimmunological tracing and radiotherapy of cancer. In the present review, the biological functions of copper in the human body are presented, along with an overview of recent progress in our understanding of the biological applications and development of copper-containing materials. Furthermore, this review also provides the prospective on the challenges of those novel biomaterials for future clinical applications.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.