Evidence map›Paper›PMID 33209946›Full record

ArticleOpen forum infectious diseases2020

Tularemia: A Case Series of Patients Diagnosed at the National Reference Center for Rickettsioses From 2008 to 2017.

Anne Darmon-Curti, François Darmon, Sophie Edouard, Aurélie Hennebique, Thomas Guimard, Guillaume Martin-Blondel, Timothée Klopfenstein, Jean-Philippe Talarmin, Didier Raoult, Max Maurin and 1 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Tularemia Antimicrobial Treatment and Prophylaxis: CDC Recommendations for Naturally Acquired Infections and Bioterrorism Response - United States, 2025.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2025
    Guideline
  2. Article
  3. Article
  4. Two cases of Francisella tularensis subspecies holartica prosthetic valve endocarditis, and review of the literature.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Review
  5. Article
  6. Non-vaccinal prophylaxis of tularemia.Frontiers in microbiology · 2024
    Review
  7. Review
  8. Review
  9. Host Immunity andMicroorganisms · 2021
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 1 country.

Anne Darmon-CurtiAix Marseille University, Institut de Recherche pour le Developpement (IRD), MEPHI, Institut Hospitalo Universitaire (IHU)-Méditerranée Infection, Marseille, France.
François DarmonLaboratoire d'Informatique Gaspard-Monge (LIGM), Unité Mixte de Recherche (UMR) 8049, Ecole des Ponts ParisTech, UPE, Marne-la-Vallée, France.
Sophie EdouardAix Marseille University, Institut de Recherche pour le Developpement (IRD), MEPHI, Institut Hospitalo Universitaire (IHU)-Méditerranée Infection, Marseille, France.
Aurélie HennebiqueCentre National de Référence des Francisella, Institut de Biologie et de Pathologie, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France.
Thomas GuimardInfectious Diseases and Emergency Department, Centre Hospitalier de La Roche sur Yon, La Roche-sur-Yon, France.
Guillaume Martin-BlondelService des Maladies Infectieuses et Tropicales, CHU de Toulouse, Toulouse, France.
Timothée KlopfensteinDepartment of Infectious Diseases, Besancon University Hospital, Besançon, France.
Jean-Philippe TalarminInternal Medicine and Infectious Diseases Department, Centre Hospitalier de Cornouaille, Quimper, France.
Didier RaoultAix Marseille University, Institut de Recherche pour le Developpement (IRD), MEPHI, Institut Hospitalo Universitaire (IHU)-Méditerranée Infection, Marseille, France.
Max MaurinCentre National de Référence des Francisella, Institut de Biologie et de Pathologie, Centre Hospitalier Universitaire Grenoble Alpes, Grenoble, France.
Pierre-Edouard FournierCentre National de Référence des Rickettsia, Coxiella et Bartonella, IHU-Méditerranée Infection, Marseille, France.
Aix-Marseille Université · FRCentre National de la Recherche Scientifique · FRCentre Hospitalier de Cornouaille · FRCentre Hospitalier Départemental Vendée · FRCentre Hospitalier Universitaire de Besançon · FRCentre Hospitalier Universitaire de Toulouse · FRInstitut de Recherche pour le Développement · FRLaboratoire d'Informatique Gaspard-Monge · FRMéditerranée Infection Foundation · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe describe the epidemiological, clinical, and prognostic aspects of 177 tularemia cases diagnosed at the National Reference Center for rickettsioses, coxiellosis, and bartonelloses between 2008 and 2017.

methodsAll patients with a microbiological diagnosis of tularemia made in the laboratory were included. Clinical and epidemiological data were collected retrospectively from clinicians in charge of patients using a standardized questionnaire. Diagnostic methods used were indirect immunofluorescence serology, real-time polymerase chain reaction (PCR), and universal PCR targeting the 16S ribosomal ribonucleic acid gene.

resultsThe series included 54 females and 123 males (sex ratio, 2.28; mean age, 47.38 years). Eighty-nine (50.2%) were confirmed as having tularemia on the basis of a positive

conclusionsOur data suggest that in an endemic area and/or in certain epidemiological contexts, tularemia should be sought to allow an optimized antibiotic therapy and a faster recovery.

Indexed as

case seriesdiagnosisFranceFrancisella tularensistularemia

Identifiers

PMID33209946
PMCPMC7651688
OpenAlexW3089046416

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.