Evidence map›Paper›PMID 33209903›Full record

ArticleAnnals of translational medicine2020

ctDNA facilitated the diagnosis of a patient with synchronous urothelial carcinoma and non-small cell lung cancer: case report.

Chengyuan Qian, Nan Dai, Mingfang Xu, Hao Luo, Yan Feng, Min Zhang, Rongrong Chen, Dong Wang

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Chengyuan QianDepartment of Cancer Center, Daping Hospital & Army Medical Center of the PLA, Chongqing, China.
Nan DaiDepartment of Cancer Center, Daping Hospital & Army Medical Center of the PLA, Chongqing, China.
Mingfang XuDepartment of Cancer Center, Daping Hospital & Army Medical Center of the PLA, Chongqing, China.
Hao LuoDepartment of Cancer Center, Daping Hospital & Army Medical Center of the PLA, Chongqing, China.
Yan FengDepartment of Cancer Center, Daping Hospital & Army Medical Center of the PLA, Chongqing, China.
Min ZhangGeneplus-Beijing, Beijing, China.
Rongrong ChenGeneplus-Beijing, Beijing, China.
Dong WangDepartment of Cancer Center, Daping Hospital & Army Medical Center of the PLA, Chongqing, China.
Army Medical University · CNDaping Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diagnosis and treatment for multiple primary cancers have been a great challenge in clinical practice. Circulating tumor DNA (ctDNA) is tumor-derived fragmented DNA that circulates in the blood. Herein we report a case that ctDNA facilitated the diagnosis of synchronous urothelial carcinoma (UC) and lung adenocarcinoma. A 58-year-old male patient was diagnosed with UC initially. Computed tomography (CT) revealed multiple metastases without the brain after surgery and adjuvant chemotherapy. However, the patient had a progressively worsened headache symbol during system therapy. We explored the genome variations using next-generation sequencing (NGS).

Indexed as

case reportCirculating tumor DNA (ctDNA)epidermal growth factor receptor (EGFR)non-small cell lung cancer (NSCLC)simultaneous cancerurothelial carcinoma (UC)

Identifiers

PMID33209903
PMCPMC7661894
OpenAlexW3097698093

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.