Evidence map›Paper›PMID 33209898›Full record

ArticleAnnals of translational medicine2020

The effect of fluid shear stress in hydrogen sulphide production and cystathionine γ-lyase expression in human early endothelial progenitor cells.

Qingsong Hu, Baojian Zhang, Yulong Liu, Yiqun Guo, Tao Zhang, Ruqiong Nie, Xiao Ke, Xiaobian Dong

Open access · diamondAbstract read
In one paragraph

Article in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Qingsong HuDepartment of Cardiology, First Affiliated Hospital of Jinan University, Guangzhou, China.
Baojian ZhangCardiac Care Unit, Affiliated Hospital of Traditional Chinese Medicine, Xinjiang Medical University, Urumqi, China.
Yulong LiuDepartment of Intervention and Vascular Surgery, First Affiliated Hospital of Jinan University, Guangzhou, China.
Yiqun GuoDepartment of Interventional Radiology and Vascular Anomalies, Guangzhou Women and Children's Medical Center, Guangzhou, China.
Tao ZhangDepartment of Cardiology, First Affiliated Hospital of Jinan University, Guangzhou, China.
Ruqiong NieDepartment of Cardiology, Guangzhou Province Key Laboratory of Arrhymia and Electrophysiology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, China.
Xiao KeDepartment of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences, Shenzhen, China.
Xiaobian DongDepartment of Cardiology, First Affiliated Hospital of Jinan University, Guangzhou, China.
First Affiliated Hospital of Jinan University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNGuangzhou Women and Children Medical Center · CNSun Yat-sen Memorial Hospital · CNXinjiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhysiological fluid shear stress has been shown to have a beneficial impact on vascular homeostasis. Endothelial progenitor cells (EPCs) make a significant contribution to maintaining endothelial integrity. Therefore, we hypothesised that shear stress-induced endothelium protection plays a role in hydrogen sulphide (H

methodsHuman EPC-derived CSE activity was detected by colorimetric assay, and H

resultsHuman EPCs were treated with shear stress levels of 5-25 dyn/cm

conclusionsThis study gives new insight into the regulatory effect of physiological shear stress on the CSE/H

Indexed as

cystathionine γ-lyase (CSE)endothelial progenitor cells (EPCs)hydrogen sulphide (H2S)Shear stress

Identifiers

PMID33209898
PMCPMC7661880
OpenAlexW3097579322

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.