Evidence map›Paper›PMID 33209870›Full record

ArticleAnnals of translational medicine2020

A comprehensive pan-cancer study of fibroblast growth factor receptor aberrations in Chinese cancer patients.

Yi Sun, Gao Li, Wei Zhu, Qiuyan He, Yongchang Liu, Xianshan Chen, Juan Liu, Jing Lin, Han Han-Zhang, Zheng Yang and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Targeting FGFR for cancer therapy.Journal of hematology & oncology · 2024
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Signaling pathways and therapeutic interventions in gastric cancer.Signal transduction and targeted therapy · 2022
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 1 country.

Yi SunDepartment of Pathology, The Second Xiangya Hospital, Central South University, Changsha, China.
Gao LiDepartment of Thoracic Surgery, Hainan General Hospital, Haikou, China.
Wei ZhuDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Qiuyan HeDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Yongchang LiuDepartment of Pathology, The Second Xiangya Hospital, Central South University, Changsha, China.
Xianshan ChenDepartment of Thoracic Surgery, Hainan General Hospital, Haikou, China.
Juan LiuWomen's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital; Nanjing, China.
Jing LinBurning Rock Biotech, Guangzhou, China.
Han Han-ZhangBurning Rock Biotech, Guangzhou, China.
Zheng YangDepartment of Pathology, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
Analyn LizasoBurning Rock Biotech, Guangzhou, China.
Jianxing XiangBurning Rock Biotech, Guangzhou, China.
Xinru MaoBurning Rock Biotech, Guangzhou, China.
Hao LiuBurning Rock Biotech, Guangzhou, China.
Yang GaoDepartment of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, China.
Burning Rock Biotech (China) · CNXiangya Hospital Central South University · CNHainan General Hospital · CNSecond Xiangya Hospital of Central South University · CNNanjing Medical University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prevalence and types of fibroblast growth factor receptor (

methodsWe retrospectively screened the genomic profiling results of 10,582 Chinese cancer patients across 16 cancer types to investigate the frequency and distribution of

results

conclusionsAmong the Chinese cancer patients in our study, the overall prevalence of

Indexed as

FGFR amplificationsFGFR fusionsFGFR mutationsFibroblast growth factor receptors (FGFRs)genomic profiling

Identifiers

PMID33209870
PMCPMC7661893
OpenAlexW3093316485

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.