ArticleJournal of thoracic disease2020
Long-term exposure to PM2.5 and Children's lung function: a dose-based association analysis.
Article in Journal of thoracic disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Impact of climate change on pediatric health outcomes.Global health action · 2026Pooled it
- Global Trends in the Relationship Between Chronic Air Pollution Exposure, Physical Activity and Lung Function in Youth Aged 5-18 Years With and Without Asthma: A Systematic Review.Sports medicine - open · 2025Pooled it
- Neighborhood-scale disparities in air exchange rates and inhaled pollution dose among school-aged children.Journal of exposure science & environmental epidemiology · 2026Article
- Asthmatic symptoms in schoolchildren: effect of PMPediatric research · 2026Article
- Lung adenocarcinoma risk in an area with seasonal high PMFrontiers in public health · 2026Article
- Association between long-term PM2.5 exposure and risk of urticaria and allergic rhinitis in Korean children: a nationwide longitudinal cohort study.Epidemiology and health · 2026Article
- Binding Multilateral Framework for South Asian Air Pollution Control: An Urgent Call for SAARC-UN Cooperation.International journal of environmental research and public health · 2025Article
- Restrictive Lung Function Patterns and Sex Differences in Primary School Children Exposed to PM2.5 in Chiang Mai, Northern Thailand.International journal of environmental research and public health · 2025Article
- Long-term PMERJ open research · 2025Article
- Children's Lung Function Was Lower in 2017-2018 than in 1995-1996: The Roles of Air Quality Change and Individual-Level Risk Factors.Environment & health (Washington, D.C.) · 2025Article
- The association between PMAIMS public health · 2025Article
- Long-term PM2.5 exposure and new-onset lung diseases among middle-aged and older adults in China: a retrospective cohort study from CHARLS.Frontiers in public health · 2025Article
- Determinants of Indoor NOToxics · 2024Article
- Article
- Short-term effect of particulate matter on lung function and impulse oscillometry system (IOS) parameters of chronic obstructive pulmonary disease (COPD) in Beijing, China.BMC public health · 2023Article
- Environmental and Behavioral Factors in Association with Lung Function Impairment in Children Living in Wuhan, China.International journal of environmental research and public health · 2023Article
- Household mold exposure in association with childhood asthma and allergic rhinitis in a northwestern city and a southern city of China.Journal of thoracic disease · 2022Article
- Epigallocatechin Gallate Relieved PM2.5-Induced Lung Fibrosis by Inhibiting Oxidative Damage and Epithelial-Mesenchymal Transition through AKT/mTOR Pathway.Oxidative medicine and cellular longevity · 2022Article
- Changes in children's lung function over two decades in relation to socioeconomic, parental and household factors in Wuhan, China.Journal of thoracic disease · 2021Article
- Respiratory health, children's lung function, and air quality in four Chinese cities: two snapshots in 1993-1996 and 2017-2018.Journal of thoracic disease · 2020Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe current literature is still not consist regarding the effect of long-term exposure to PM2.5 and children's lung function, partly due to inadequate or inaccurate exposure assessment. In this study, we aim to investigate the associations between long-term exposure to PM2.5, estimated as average daily dose (ADD), and lung function in school-age children.
methodsWe recruited 684 participants of 7-12 years old from the city of Lanzhou located in northwestern China. Participants underwent spirometric tests for lung function and responded to a questionnaire survey. Detailed information about individual air exposure and personal information were collected, including length of school hours, home address, age, gender, etc. Combining the spatial distribution of PM2.5 concentrations in the past 5 years and individual time-activity data, we estimated annual ADD for 5 years preceding the lung function tests and 5-year average ADD, respectively. We used multiple linear regression models to examine the associations between ADD values and lung function, controlling for a range of individual-level covariates.
resultsThe 5-year average ADD among all the participants was 50.5 µg/kg-d, with higher values estimated for children living in the urban area than the suburban area, for boys than girls, and for children whose parents received a lower education attainment. We found that a 1 μg/kg-d increment in ADD of PM2.5 was associated with a 10.49 mL (95% CI: -20.47, -0.50) decrease in forced vital capacity (FVC) and a 7.68 mL (95% CI: -15.80, -0.44) decrease in forced exploratory volume in 1 second (FEV
conclusionsLong-term PM2.5 exposure, when estimated as exposure dose averaged over a year or longer, was associated with statistically significant reductions in FVC and FEV1 in children of elementary-school age. Future studies may consider the use of individual-level dose estimates (as opposed to exposure concentrations) to improve the dose-response assessment.
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