Evidence map›Paper›PMID 33209464›Full record

ReviewJournal of thoracic disease2020

Paraneoplastic syndromes in small cell lung cancer.

Zaid Soomro, Michael Youssef, Shlomit Yust-Katz, Ali Jalali, Akash J Patel, Jacob Mandel

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of thoracic disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.

  1. Pooled it
  2. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Article
  3. Paraneoplastic neurologic syndrome in a 65-year-old woman with small cell lung cancer.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
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  18. Accelerating and protective effects toward cancer growth in cGAS and FcgRIIb deficient mice, respectively, an impact of macrophage polarization.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Zaid SoomroUniversity of Texas MD Anderson Cancer Center, Houston, TX, USA.
Michael YoussefUniversity of Texas MD Anderson Cancer Center, Houston, TX, USA.
Shlomit Yust-KatzRabin Medical Center, Petach Tikva, Israel.
Ali JalaliDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, USA.
Akash J PatelDepartment of Neurosurgery, Baylor College of Medicine, Houston, TX, USA.
Jacob MandelDepartment of Neurology, Baylor College of Medicine, Houston, TX, USA.
Baylor College of Medicine · USThe University of Texas MD Anderson Cancer Center · USRabin Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paraneoplastic syndromes can commonly occur due to lung cancer, especially small cell lung cancer. Frequently paraneoplastic syndromes can precede the diagnosis of the neoplasm or present with limited stage disease. However, these syndromes can also occur at the time of recurrence or metastasis of disease. This review focuses on the epidemiology, pathogenesis, clinical features, and current management of the most common paraneoplastic syndromes encountered in patients with small cell lung cancer. Manifestations of paraneoplastic syndromes in small cell lung cancer include endocrine syndromes with secretion of excess hormones, and neurologic syndromes due to the production of antibodies causing an autoimmune condition. Recent advances have allowed for greater understanding of these syndromes and for the development of improved diagnostic as well as therapeutic tools. Awareness of paraneoplastic syndromes in small cell lung cancer can lead to an earlier diagnosis and recognition of both the condition and in some cases the disease potentially improving the overall survival and prognosis for patients. Further research examining effective methods to improve recovery from neurologic deficits in patients with a paraneoplastic neurologic illness is warranted.

Indexed as

paraneoplastic endocrine syndromesparaneoplastic neurologic syndromesParaneoplastic syndromesmall cell lung cancer (SCLC)

Identifiers

PMID33209464
PMCPMC7656388
OpenAlexW3018831200

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.