Evidence map›Paper›PMID 33209424›Full record

ArticleJournal of thoracic disease2020

Patient motivations for non-adherence to lung cancer screening in a military population.

Kenneth P Seastedt, Michael J Luca, Jared L Antevil, Robert F Browning, Philip S Mullenix, Junewai L Reoma, Sean A McKay

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Patient Adherence to Lung CT Screening Reporting & Data System-Recommended Screening Intervals in the United States: A Systematic Review and Meta-Analysis.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2022
    Pooled it
  3. Review
  4. Article
  5. Article
  6. Adherence to Lung Cancer Screening: What Exactly Are We Talking About?Annals of the American Thoracic Society · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kenneth P SeastedtDepartment of Surgery, USUHS F. Edward Hébert School of Medicine, Bethesda, MD, USA.
Michael J LucaDepartment of Pulmonology, USUHS F. Edward Hébert School of Medicine, Bethesda, MD, USA.
Jared L AntevilDepartment of Cardiothoracic Surgery, Veterans Affairs Medical Center, Washington, DC, USA.
Robert F BrowningDepartment of Pulmonology, Division of Interventional Pulmonology, USUHS F. Edward Hébert School of Medicine, Bethesda, MD, USA.
Philip S MullenixDepartment of Cardiothoracic Surgery, USUHS F. Edward Hébert School of Medicine, Bethesda, MD, USA.
Junewai L ReomaDepartment of Cardiothoracic Surgery, USUHS F. Edward Hébert School of Medicine, Bethesda, MD, USA.
Sean A McKayDepartment of Pulmonology, USUHS F. Edward Hébert School of Medicine, Bethesda, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLung cancer remains the leading cause of cancer deaths in the United States, and lung cancer screening has been shown to decrease this mortality. Adherence to lung cancer screening is paramount to realize the mortality benefit, and reported adherence rates vary widely. Few reports address non-adherence to screening, and our study sought to understand the non-compliant patients in our military population.

methodsThis Institutional Review Board approved retrospective review of patients enrolled in our screening program from 2013-2019 identified patients who failed to obtain a subsequent Low Dose CT scan (LDCT) within 15 months of their prior scan. Attempts were made to contact these patients and elucidate motivations for non-adherence via telephone.

resultsOf the 242 patients enrolled, 183 (76%) patients were adherent to the protocol. Significant predictors of non-adherence versus adherence were younger age (P=0.008), female sex (P=0.005), and enlisted officer rank (P=0.03). There was no difference with regards to race, smoking status, pack-years, negative screens, lung-RADS level, or nodule size. 31 (52%) non-adherent patients were contacted, and 24 (77%) reported their reason for non-adherence was lack of follow-up for a LDCT. Twenty (64%) were interested in re-enrollment. Of the total screening cohort, 15 interventions were performed, with lung cancer identified in 5 (2%)-a 67% false positive rate. One stage IV lung cancer was found in a non-adherent patient who re-enrolled.

conclusionsLack of perceived contact for follow-up was expressed as the primary reason for non-compliance in our screening program. Compliance is critical to the efficacy of any screening modality, and adherence rates to lung cancer screening may be increased through improved contact with patients via multiple avenues (i.e., phone, email, and letter). There is benefit in contacting non-adherent patients as high rates of re-enrollment are possible.

Indexed as

adherenceenrollmentlow dose CT scan (LDCT)Lung cancer screeningsmoking

Identifiers

PMID33209424
PMCPMC7656399

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.