Evidence map›Paper›PMID 33209403›Full record

ArticleJournal of thoracic disease2020

Economic evaluation of the specialized donor care facility for thoracic organ donor management.

Jason M Gauthier, Maria B Majella Doyle, William C Chapman, Gary Marklin, Chad A Witt, Elbert P Trulock, Derek E Byers, Ramsey R Hachem, Michael K Pasque, Bryan F Meyers and 6 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of thoracic disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Characterizing proximity and transfers of deceased organ donors to donor care units in the United States.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024
    Article
  5. Article
  6. Review
  7. Article
  8. Same-teams versus different-teams for long distance lung procurement: A cost analysis.The Journal of thoracic and cardiovascular surgery · 2023
    Article
  9. Different-team procurements: A potential solution for the unintended consequences of change in lung allocation policy.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Jason M GauthierDivision of Cardiothoracic Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Maria B Majella DoyleDivision of Abdominal Organ Transplantation, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
William C ChapmanDivision of Abdominal Organ Transplantation, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Gary MarklinMid-America Transplant, Washington University School of Medicine, Saint Louis, MO, USA.
Chad A WittDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, Saint Louis, MO, USA.
Elbert P TrulockDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, Saint Louis, MO, USA.
Derek E ByersDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, Saint Louis, MO, USA.
Ramsey R HachemDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, Saint Louis, MO, USA.
Michael K PasqueDivision of Cardiothoracic Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Bryan F MeyersDivision of Cardiothoracic Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
G Alexander PattersonDivision of Cardiothoracic Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Ruben G NavaDivision of Cardiothoracic Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Benjamin D KozowerDivision of Cardiothoracic Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Daniel KreiselDivision of Cardiothoracic Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Su-Hsin ChangDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Varun PuriDivision of Cardiothoracic Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
Washington University in St. Louis · US

Funding

Optimizing Donor Management in Lung TransplantationR01HL146856 · NHLBI · WASHINGTON UNIVERSITY · PI Ana Baumann Walker, Matthew Galen Hartwig · 2020 to 2026
$2.7M
MODELING THE COEXISTENCE OF CHRONIC DISEASES RELATED TO OBESITYR21DK110530 · NIDDK · WASHINGTON UNIVERSITY · PI CHANG, SU-HSIN · 2017 to 2018
$419k
Innate Immune Mechanisms of Ischemia Reperfusion Injury Following Cardiac TransplantationF32HL143950 · NHLBI · WASHINGTON UNIVERSITY · PI GAUTHIER, JASON MICHAEL · 2018 to 2018
$60k
NHLBI NIH HHS F32 HL143950NHLBI NIH HHS R01 HL146856NIDDK NIH HHS R21 DK110530
6 · The paper itself

Abstract

backgroundOver the last decade two alternative models of donor care have emerged in the United States: the conventional model, whereby donors are managed at the hospital where brain death occurs, and the specialized donor care facility (SDCF), in which brain dead donors are transferred to a SDCF for medical optimization and organ procurement. Despite increasing use of the SDCF model, its cost-effectiveness in comparison to the conventional model remains unknown.

methodsWe performed an economic evaluation of the SDCF and conventional model of donor care from the perspective of U.S. transplant centers over a 2-year study period. In this analysis, we utilized nationwide data from the Scientific Registry of Transplant Recipients and controlled for donor characteristics and patterns of organ sharing across the nation's organ procurement organizations (OPOs). Subgroup analysis was performed to determine the impact of the SDCF model on thoracic organ transplants.

resultsA total of 38,944 organ transplants were performed in the U.S. during the study period from 13,539 donors with an observed total organ cost of $1.36 billion. If every OPO assumed the cost and effectiveness of the SDCF model, a predicted 39,155 organ transplants (+211) would have been performed with a predicted total organ cost of $1.26 billion (-$100 million). Subgroup analysis of thoracic organs revealed that the SDCF model would lead to a predicted 156 additional transplants with a cost saving of $24.6 million.

conclusionsThe U.S. SDCF model may be a less costly and more effective means of multi-organ donor management, particularly for thoracic organ donors, compared to the conventional hospital-based model.

Indexed as

lungOrgan donor managementtransplantationtransplantation, heart

Identifiers

PMID33209403
PMCPMC7656378
OpenAlexW3084807521

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.