Evidence map›Paper›PMID 33209195›Full record

ArticleAnimal cells and systems2020

Treatment of growth hormone attenuates hepatic steatosis in hyperlipidemic mice via downregulation of hepatic CD36 expression.

Hyung Seok Jang, Kyeongdae Kim, Mi-Ran Lee, Shin-Hye Kim, Jae-Hoon Choi, Mi Jung Park

Open access · goldAbstract read
In one paragraph

Article in Animal cells and systems, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Hyung Seok JangDepartment of Life Science, College of Natural Sciences and Research Institute for Natural Sciences, Hanyang University, Seoul, Republic of Korea.
Kyeongdae KimDepartment of Life Science, College of Natural Sciences and Research Institute for Natural Sciences, Hanyang University, Seoul, Republic of Korea.
Mi-Ran LeeDepartment of Biomedical Laboratory Science, Jungwon University, Goesan, Republic of Korea.
Shin-Hye KimDepartment of Pediatrics, Inje University Sanggye Paik Hospital, Seoul, Republic of Korea.
Jae-Hoon ChoiDepartment of Life Science, College of Natural Sciences and Research Institute for Natural Sciences, Hanyang University, Seoul, Republic of Korea.
Mi Jung ParkDepartment of Pediatrics, Inje University Sanggye Paik Hospital, Seoul, Republic of Korea.
Hanyang University · KRInje University Sanggye Paik Hospital · KRJungwon University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recombinant human growth hormone (GH) has been used for the treatment of growth hormone deficiency (GHD) and diverse short stature state, and its physiological and therapeutic effects are well documented. However, since the effect of GH treatment on metabolic disorders has not been well characterized, we injected GH to Western diet-fed low-density lipoprotein receptor-deficient (

Indexed as

atherosclerosisCD36Growth hormonehepatic steatosishyperlipidemia

Identifiers

PMID33209195
PMCPMC7651854
OpenAlexW3035698079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.