Evidence map›Paper›PMID 33208518›Full record

ArticlemSphere2020

Functional Characterization of Circulating Mumps Viruses with Stop Codon Mutations in the Small Hydrophobic Protein.

Rita Czakó Stinnett, Andrew S Beck, Elena N Lopareva, Rebecca J McNall, Donald R Latner, Carole J Hickman, Paul A Rota, Bettina Bankamp

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Small hydrophobic (SH) proteins ofJournal of virology · 2024
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Rita Czakó StinnettDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID 0000-0001-8686-0260
Andrew S BeckOak Ridge Institute for Science and Education (ORISE), contracted to Division of Viral Diseases, Centers for Disease Control and Prevention, Oak Ridge, Tennessee, USA.ORCID 0000-0001-5307-5565
Elena N LoparevaDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Rebecca J McNallDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Donald R LatnerDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Carole J HickmanDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Paul A RotaDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Bettina BankampDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA bfb9@cdc.gov.ORCID 0000-0002-0846-3320
Centers for Disease Control and Prevention · USOak Ridge Associated Universities · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Between 2015 and 2017, routine molecular surveillance in the United States detected multiple mumps viruses (MuVs) with mutations in the small hydrophobic (SH) gene compared to a reference virus of the same genotype. These mutations include an unusual pattern of uracil-to-cytosine hypermutations and other mutations resulting in the generation of premature stop codons or disruption of the canonical stop codon. The mumps virus SH protein may serve as a virulence factor, based on evidence that it inhibits apoptosis and innate immune signaling

Indexed as

MutationAnimalsCodon, TerminatorHumansMeaslesMumps virusViral ProteinsVirulenceVirulence FactorsCodon, Terminatorsmall hydrophobic protein, Mumps virusViral ProteinsVirulence Factorsaltered terminationgenomicshost-pathogen interactionsmolecular epidemiologymumps virusnext-generation sequencingparamyxovirusSH proteinsurveillance studiesvaccinevaccine preventable

Identifiers

PMID33208518
PMCPMC7677008
OpenAlexW3104847640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.