Evidence map›Paper›PMID 33208514›Full record

ArticlemSphere2020

Assessment of

Luisa W Hugerth, Marcela Pereira, Yinghua Zha, Maike Seifert, Vilde Kaldhusdal, Fredrik Boulund, Maria C Krog, Zahra Bashir, Marica Hamsten, Emma Fransson and 3 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in mSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 26 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Group BFrontiers in cellular and infection microbiology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Luisa W HugerthCentre for Translational Microbiome Research, Department of Microbiology, Tumour and Cell Biology, Science for Life Laboratory, Karolinska Institutet, Solna, Sweden.ORCID 0000-0001-5432-1764
Marcela PereiraCentre for Translational Microbiome Research, Department of Microbiology, Tumour and Cell Biology, Science for Life Laboratory, Karolinska Institutet, Solna, Sweden.
Yinghua ZhaCentre for Translational Microbiome Research, Department of Microbiology, Tumour and Cell Biology, Science for Life Laboratory, Karolinska Institutet, Solna, Sweden.
Maike SeifertCentre for Translational Microbiome Research, Department of Microbiology, Tumour and Cell Biology, Science for Life Laboratory, Karolinska Institutet, Solna, Sweden.
Vilde KaldhusdalDepartment of Medicine Solna, Division of Infectious Diseases, Karolinska University Hospital, Center for Molecular Medicine, Karolinska Institutet, Solna, Sweden.
Fredrik BoulundCentre for Translational Microbiome Research, Department of Microbiology, Tumour and Cell Biology, Science for Life Laboratory, Karolinska Institutet, Solna, Sweden.
Maria C KrogThe Recurrent Pregnancy Loss Unit, Capital Region of Denmark, Rigshospitalet and Hvidovre Hospital, Copenhagen, Denmark.
Zahra BashirThe Recurrent Pregnancy Loss Unit, Capital Region of Denmark, Rigshospitalet and Hvidovre Hospital, Copenhagen, Denmark.
Marica HamstenCentre for Translational Microbiome Research, Department of Microbiology, Tumour and Cell Biology, Science for Life Laboratory, Karolinska Institutet, Solna, Sweden.
Emma FranssonCentre for Translational Microbiome Research, Department of Microbiology, Tumour and Cell Biology, Science for Life Laboratory, Karolinska Institutet, Solna, Sweden.
Henriette Svarre-NielsenThe Recurrent Pregnancy Loss Unit, Capital Region of Denmark, Rigshospitalet and Hvidovre Hospital, Copenhagen, Denmark.
Ina Schuppe-KoistinenCentre for Translational Microbiome Research, Department of Microbiology, Tumour and Cell Biology, Science for Life Laboratory, Karolinska Institutet, Solna, Sweden.
Lars EngstrandCentre for Translational Microbiome Research, Department of Microbiology, Tumour and Cell Biology, Science for Life Laboratory, Karolinska Institutet, Solna, Sweden lars.engstrand@ki.se.ORCID 0000-0002-7713-2373
Science for Life Laboratory · SEHvidovre Hospital · DKKarolinska University Hospital · SEUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The vaginal microbiome has been connected to a wide range of health outcomes. This has led to a thriving research environment but also to the use of conflicting methodologies to study its microbial composition. Here, we systematically assessed best practices for the sequencing-based characterization of the human vaginal microbiome. As far as 16S rRNA gene sequencing is concerned, the V1-V3 region performed best

Indexed as

MetagenomeMicrobiotaComputational BiologyComputer SimulationDatabases, GeneticFemaleHumansMetagenomicsRNA, Ribosomal, 16SSequence Analysis, DNAVaginaRNA, Ribosomal, 16S16S rRNAampliconhuman microbiomemetagenomicsmolecular methodsPCRquantitative methodsvaginal microbiome

Identifiers

PMID33208514
PMCPMC7677004
OpenAlexW3099404770

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.