ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021
HIFα Regulates Developmental Myelination Independent of Autocrine Wnt Signaling.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 21 citations in OpenAlex.
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- A paradigm shift of SERPINA3N in neurobehavioral development and brain injury.bioRxiv : the preprint server for biology · 2025Article
- Transcription factor 7-like 2 (TCF7l2) regulates CNS myelination separating from its role in upstream oligodendrocyte differentiation.Journal of neurochemistry · 2025Article
- Potential Role of Endoplasmic Reticulum Stress in Modulating Protein Homeostasis in Oligodendrocytes to Improve White Matter Injury in Preterm Infants.Molecular neurobiology · 2024Review
- Role of the Gut Microbiota-Brain Axis in Brain Damage in Preterm Infants.ACS pharmacology & translational science · 2024Review
- Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood-brain barrier impairment.Acta neuropathologica communications · 2023Article
- Cerebral Myelination in a Bronchopulmonary Dysplasia Murine Model.Children (Basel, Switzerland) · 2023Article
- Hypoxia-Inducible Pathway Polymorphisms and Their Role in the Complications of Prematurity.Genes · 2023Article
- DLP-printed GelMA-PMAA scaffold for bone regeneration through endochondral ossification.International journal of bioprinting · 2023Article
- A Simplified Paradigm of Late Gestation Transient Prenatal Hypoxia to Investigate Functional and Structural Outcomes from a Developmental Hypoxic Insult.Bio-protocol · 2022Article
- Deficits in Seizure Threshold and Other Behaviors in Adult Mice without Gross Neuroanatomic Injury after Late Gestation Transient Prenatal Hypoxia.Developmental neuroscience · 2022Article
- Hypoxia inducible factor and diffuse white matter injury in the premature brain: perspectives from genetic studies in mice.Neural regeneration research · 2022Article
- Ablating the Transporter Sodium-Dependent Dicarboxylate Transporter 3 Prevents Leukodystrophy in Canavan Disease Mice.Annals of neurology · 2021Article
- PARP1-mediated PARylation activity is essential for oligodendroglial differentiation and CNS myelination.Cell reports · 2021Article
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Authors and funding
6 authors at 3 institutions in 1 country.
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Abstract
The developing CNS is exposed to physiological hypoxia, under which hypoxia-inducible factor α (HIFα) is stabilized and plays a crucial role in regulating neural development. The cellular and molecular mechanisms of HIFα in developmental myelination remain incompletely understood. A previous concept proposes that HIFα regulates CNS developmental myelination by activating the autocrine Wnt/β-catenin signaling in oligodendrocyte progenitor cells (OPCs). Here, by analyzing a battery of genetic mice of both sexes, we presented
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