ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021
Arrangement of Excitatory Synaptic Inputs on Dendrites of the Medial Superior Olive.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- Nonlinear Dendritic Integration Supports Up-Down States in Single Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- A mammalian inferior colliculus model for sound source separation using interaural time differences.PLoS computational biology · 2025Article
- Oligodendrocyte arrangement, identification and morphology in the developing superior olivary complex.Frontiers in cellular neuroscience · 2025Article
- Cellular and synaptic specializations for sub-millisecond precision in the mammalian auditory brainstem.Frontiers in cellular neuroscience · 2025Review
- Anatomy of superior olivary complex and lateral lemniscus in Etruscan shrew.Scientific reports · 2024Article
- Developmental fine-tuning of medial superior olive neurons mitigates their predisposition to contralateral sound sources.PLoS biology · 2024Article
- Neuronal morphology and synaptic input patterns of neurons in the intermediate nucleus of the lateral lemniscus of gerbils.Scientific reports · 2023Article
- Endogenous Modulators of NMDA Receptor Control Dendritic Field Expansion of Cortical Neurons.Molecular neurobiology · 2023Article
- Mammalian octopus cells are direction selective to frequency sweeps by excitatory synaptic sequence detection.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Cellular Strategies for Frequency-Dependent Computation of Interaural Time Difference.Frontiers in synaptic neuroscience · 2022Review
- Periodicity Pitch Perception Part III: Sensibility and Pachinko Volatility.Frontiers in neuroscience · 2022Article
- Dendritic synapse geometry optimizes binaural computation in a sound localization circuit.Science advances · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neurons in the medial superior olive (MSO) detect 10 µs differences in the arrival times of a sound at the two ears. Such acuity requires exquisitely precise integration of binaural synaptic inputs. There is substantial understanding of how neuronal phase locking of afferent MSO structures, and MSO membrane biophysics subserve such high precision. However, we still lack insight into how the entirety of excitatory inputs is integrated along the MSO dendrite under sound stimulation. To understand how the dendrite integrates excitatory inputs as a whole, we combined anatomic quantifications of the afferent innervation in gerbils of both sexes with computational modeling of a single cell. We present anatomic data from confocal and transmission electron microscopy showing that single afferent fibers follow a single dendrite mostly up to the soma and contact it at multiple (median 4) synaptic sites, each containing multiple independent active zones (the overall density of active zones is estimated as 1.375 per μm
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.