ArticleDental materials : official publication of the Academy of Dental Materials2021
Biofilm and cell adhesion strength on dental implant surfaces via the laser spallation technique.
Article in Dental materials : official publication of the Academy of Dental Materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 28 citations in OpenAlex.
- Adhesion index integrates cell and bacterial responses to titanium across protein conditioning and surface roughness.Biofilm · 2026Article
- Antimicrobial effect of plantago major extract against streptococcus mutans in dental caries formation.Brazilian dental journal · 2026Article
- Does proper flossing performance translate into effective plaque removal?Clinical oral investigations · 2025Article
- Improvement of cellular pattern organization and clarity through centrifugal force.Biomedical materials (Bristol, England) · 2025Article
- In-vitro simulation methods for mechanical plaque removal: a systematic scoping review of current techniques and future directions.BMC oral health · 2025Article
- Sucrose-mediated formation and adhesion strength ofBiofilm · 2023Article
- Article
- Nitrilotriacetic Acid Improves Plasma Electrolytic Oxidation of Titanium for Biomedical Applications.ACS applied materials & interfaces · 2023Article
- 3D-printed mesoporous bioactive glass/GelMA biomimetic scaffolds for osteogenic/cementogenic differentiation of periodontal ligament cells.Frontiers in bioengineering and biotechnology · 2022Article
- Evolution of the Laser-Induced Spallation Technique in Film Adhesion Measurement.Applied mechanics reviews · 2021Review
- Biofilm and cell adhesion strength on dental implant surfaces via the laser spallation technique.Dental materials : official publication of the Academy of Dental Materials · 2021Article
- Response of NIH 3T3 Fibroblast Cells on Laser-Induced Periodic Surface Structures on a 15×(Ti/Zr)/Si Multilayer System.Nanomaterials (Basel, Switzerland) · 2020Article
- The effect of surface roughness on laser-induced stress wave propagation.Applied physics letters · 2020Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectiveThe aims of this study are to quantify the adhesion strength differential between an oral bacterial biofilm and an osteoblast-like cell monolayer to a dental implant-simulant surface and develop a metric that quantifies the biocompatible effect of implant surfaces on bacterial and cell adhesion.
methodsHigh-amplitude short-duration stress waves generated by laser pulse absorption are used to spall bacteria and cells from titanium substrates. By carefully controlling laser fluence and calibration of laser fluence with applied stress, the adhesion difference between Streptococcus mutans biofilms and MG 63 osteoblast-like cell monolayers on smooth and rough titanium substrates is obtained. The ratio of cell adhesion strength to biofilm adhesion strength (i.e., Adhesion Index) is determined as a nondimensionalized parameter for biocompatibility assessment.
resultsAdhesion strength of 143 MPa, with a 95% C.I. (114, 176), is measured for MG 63 cells on smooth titanium and 292 MPa, with a 95% C.I. (267, 306), on roughened titanium. Adhesion strength for S. mutans on smooth titanium is 320 MPa, with a 95% C.I. (304, 333), and remained relatively constant at 332 MPa, with a 95% C.I. (324, 343), on roughened titanium. The calculated Adhesion Index for smooth titanium is 0.451, with a 95% C.I. (0.267, 0.622), which increased to 0.876, with a 95% C.I. (0.780, 0.932), on roughened titanium. SIGNIFICANCE: The laser spallation technique provides a platform to examine the tradeoffs of adhesion modulators on both biofilm and cell adhesion. This tradeoff is characterized by the Adhesion Index, which is proposed to aid biocompatibility screening and could help improve implantation outcomes. The Adhesion Index is implemented to determine surface factors that promote favorable adhesion of cells greater than biofilms. Here, an Adhesion Index ≫ 1 suggests favorable biocompatibility.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.