Evidence map›Paper›PMID 33208167›Full record

ArticleNutrition journal2020

Garlic (Allium sativum L.): a potential unique therapeutic food rich in organosulfur and flavonoid compounds to fight with COVID-19.

Sucheta Khubber, Reza Hashemifesharaki, Mehrdad Mohammadi, Seyed Mohammad Taghi Gharibzahedi

Open access · goldAbstract readLetter
In one paragraph

Article in Nutrition journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
22.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 120 citations in OpenAlex.

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  7. Foods (Basel, Switzerland) · 2024
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  19. Paving New Roads UsingIranian journal of pharmaceutical research : IJPR · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Sucheta KhubberCenter of Innovative and Applied Bioprocessing, Mohali, 140306, India.
Reza HashemifesharakiDepartment of Research and Development, Nova Harmony LLC, Santa Monica, California, USA.
Mehrdad MohammadiDepartment of Food Technology Research, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Seyed Mohammad Taghi GharibzahediYoung Researchers and Elite Club, Lahijan Branch, Islamic Azad University, Lahijan, Iran. smt.gharibzahedi@gmail.com.
Chaudhary Charan Singh Haryana Agricultural University · INIslamic Azad University, Lahijan Branch · IRShahid Beheshti University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) is the current major health crisis in the world. A successful strategy to combat the COVID-19 pandemic is the improvement of nutritional pattern. Garlic is one of the most efficient natural antibiotics against the wide spectrum of viruses and bacteria. Organosulfur (e.g., allicin and alliin) and flavonoid (e.g., quercetin) compounds are responsible for immunomodulatory effects of this healthy spice. The viral replication process is accelerated with the main structural protease of SARS-CoV-2. The formation of hydrogen bonds between this serine-type protease and garlic bioactives in the active site regions inhibits the COVID-19 outbreak. The daily dietary intake of garlic and its derived-products as an adjuvant therapy may improve side effects and toxicity of the main therapeutic drugs with reducing the used dose.

Indexed as

GarlicCOVID-19CysteineDisulfidesFlavonoidsFunctional FoodHumansPandemicsPlant ExtractsSulfinic AcidsallicinalliinCysteineDisulfidesFlavonoidsPlant ExtractsSulfinic AcidsAllicinAntiviralCOVID-19GarlicQuercetinSARS-CoV-2

Identifiers

PMID33208167
PMCPMC7673072
OpenAlexW3098680187

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.