ArticleJournal of nanobiotechnology2020
Effect of silica-coated magnetic nanoparticles on rigidity sensing of human embryonic kidney cells.
Article in Journal of nanobiotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
14 citing papers in PubMed, 40 citations in OpenAlex.
- Integrated omics-driven discovery reveals synphilin-1-mediated anoikis resistance through p53 down-regulation.Bioscience reports · 2026Article
- Submicron traction-force mapping reveals mitochondrial regulation of nanoscale force coordination during rigidity sensing under oxidative stress.Nano convergence · 2026Article
- Synphilin-1 regulates mechanotransduction in rigidity sensing through interaction with zyxin.Journal of nanobiotechnology · 2025Article
- A Comparative and Critical Analysis for In Vitro Cytotoxic Evaluation of Magneto-Crystalline Zinc Ferrite Nanoparticles Using MTT, Crystal Violet, LDH, and Apoptosis Assay.International journal of molecular sciences · 2023Article
- Mechanobiological Analysis of Nanoparticle Toxicity.Nanomaterials (Basel, Switzerland) · 2023Review
- Systematic and Bibliometric Analysis of Magnetite Nanoparticles and Their Applications in (Biomedical) Research.Global challenges (Hoboken, NJ) · 2023Article
- Quantifying intracellular trafficking of silica-coated magnetic nanoparticles in live single cells by site-specific direct stochastic optical reconstruction microscopy.Journal of nanobiotechnology · 2021Article
- Silica-coated magnetic-nanoparticle-induced cytotoxicity is reduced in microglia by glutathione and citrate identified using integrated omics.Particle and fibre toxicology · 2021Article
- Analysis of Nanotoxicity with Integrated Omics and Mechanobiology.Nanomaterials (Basel, Switzerland) · 2021Review
- Review
- Silica-coated magnetic nanoparticles activate microglia and induce neurotoxic D-serine secretion.Particle and fibre toxicology · 2021Article
- Advantages and Disadvantages of Using Magnetic Nanoparticles for the Treatment of Complicated Ocular Disorders.Pharmaceutics · 2021Review
- Probing mechanobiological role of filamin A in migration and invasion of human U87 glioblastoma cells using submicron soft pillars.Nano convergence · 2021Article
- Decrease in membrane fluidity and traction force induced by silica-coated magnetic nanoparticles.Journal of nanobiotechnology · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundNanoparticles (NPs) can enter cells and cause cellular dysfunction. For example, reactive oxygen species generated by NPs can damage the cytoskeleton and impair cellular adhesion properties. Previously, we reported that cell spreading and protrusion structures such as lamellipodia and filopodia was reduced when cells are treated with silica-coated magnetic nanoparticles incorporating rhodamine B isothiocyanate (MNPs@SiO
resultsHere, we report that the rigidity sensing of human embryonic kidney (HEK293) cells was impaired even at 0.1 μg/μL of MNPs@SiO
conclusionsOur results suggest that NPs may impair the rigidity sensing of cells even at low concentrations, thereby affecting cell adhesion and spreading.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.