ArticleBMC nephrology2020
Assessment of serum electrolytes and kidney function test for screening of chronic kidney disease among Ethiopian Public Health Institute staff members, Addis Ababa, Ethiopia.
Article in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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13 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Major electrolyte disorder and associated factors among patients with chronic disease in Ethiopia: a systematic review and meta-analysis.BMC nephrology · 2024Pooled it
- A Comparative Study between Serum Cystatin C and Microalbuminuria in the Diagnosis of Nephropathy in Type 2 Diabetes Mellitus.Annals of African medicine · 2026Article
- Serum electrolyte disturbances and treatment outcomes in hospitalized children with Severe Acute Malnutrition in Ethiopia.Scientific reports · 2026Article
- 90-Day Subchronic Toxicological Evaluation of a Zylaria in Sprague Dawley Rats.Journal of toxicology · 2026Article
- The combined effects of extended feeding with a high level of Arthrospira platensis and a commercial enzyme mix or porcine pancreatin on broilers' blood cells, plasma metabolites and liver lipid profile.BMC veterinary research · 2025Article
- Blood Pressure Control and Associated Factors among Hypertension Comorbid Type 2 Diabetic Patients in Southeast Ethiopia.International journal of hypertension · 2024Article
- Impact of high Spirulina diet, extruded or supplemented with enzymes, on blood cells, systemic metabolites, and hepatic lipid and mineral profiles of broiler chickens.Frontiers in veterinary science · 2024Article
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- Mercuric Chloride Induced Nephrotoxicity: Ameliorative Effect ofACS omega · 2023Article
- Dietary Ulva lactuca and CAZyme supplementation improve serum biochemical profile and hepatic composition of weaned piglets.Scientific reports · 2023Article
- Effect of Laminaria digitata dietary inclusion and CAZyme supplementation on blood cells, serum metabolites and hepatic lipids and minerals of weaned piglets.Scientific reports · 2023Article
- Assessment of serum biochemical derangements and associated risk factors of chronic kidney disease.Journal of Taibah University Medical Sciences · 2022Article
- Solving the Puzzle of Global Health Inequity: Completing the Picture Piece by Piece by Piece.Global implementation research and applications · 2021Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic kidney disease (CKD), which is characterized by its asymptomatic nature until an end stage, is one of the most common public health problems in the world. Thus, a regular checkup, especially for those individuals with high risk groups is inevitably important, and the screening has been done with laboratory findings. However, in developing countries, including Ethiopia screening for CKD are rarely done, and it is becoming common to hear sudden death from the kidney failure. Therefore, we aimed to screen serum electrolyte levels and estimated glomerular filtration rate (eGFR) among Ethiopian Public Health Institute (EPHI) staff members for an early detection of CKD and to identify the factors associated with it.
methodsA cross-sectional study was conducted from July 1 to October 28, 2018 among EPHI staff members. The level of serum creatinine and electrolytes were measured using COBAS 6000 analyzer. Then, eGFR was calculated using MDRD and CKD-EPI equations. Data analysis were done using SPSS version 20, and the factors associated with the outcome variable were assessed using logistic regression. P values < 0.05 were considered as statistically significant.
resultsThis study found that 3.6 and 1.9% of the study participants were at CKD stage II by MDRD and CKD-EPI equations, respectively. Out of the total study participants, 9.5% had hyperkalemia (serum potassium level > 5.0 mmol/L) and 8.5% had hypocalcemia (serum calcium level < 2.15 mmol/L). An older age (P = 0.006), high BMI (P = 0.045) and previous history of CVDs (P = 0.033) were found to be significantly associated factors with reduced glomerular filtration rate. Nine percent of the study participants were obese, 6.1% had family history of kidney failure, 18% self-reported history of hypertension, 3.4% diabetic and 5.3% had CVDs. About 51.2% of the study participants were males, and the majorities, (66%) of the study participants were found to be alcohol consumers.
conclusionsThe prevalence of a stage II kidney disease was relatively low and none of the participants was under serious kidney disease (GFR < 60 mmol/min/1.73m
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