ArticleJournal of the American Heart Association2020
Dysfunctional Mitochondrial Dynamic and Oxidative Phosphorylation Precedes Cardiac Dysfunction in R120G-αB-Crystallin-Induced Desmin-Related Cardiomyopathy.
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Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
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Who cites it
21 citing papers in PubMed, 27 citations in OpenAlex.
- Mitophagy Facilitates Cytosolic Proteostasis to Preserve Cardiac Function.Circulation research · 2026Article
- The R120G knock-in mutation in αB-crystallin is insufficient to induce cardiomyopathy in mice.American journal of physiology. Heart and circulatory physiology · 2026Article
- Redox Imbalance and Genetic Mutations in Heart Failure: Synergistic Mechanisms and Therapeutic Strategies.Genes · 2026Review
- A Micro-Engineered Heart Tissue Model of Desmin-related Cardiomyopathy Caused by Mutant αB Crystallin.bioRxiv : the preprint server for biology · 2025Article
- TANGO2 binds crystallin alpha B and its loss causes desminopathy.Nature communications · 2025Article
- WTAP-mediated mRedox report : communications in free radical research · 2024Article
- Diastolic dysfunction in Alzheimer's disease model mice is associated with Aβ-amyloid aggregate formation and mitochondrial dysfunction.Scientific reports · 2024Article
- Exploring Anthracycline-Induced Cardiotoxicity from the Perspective of Protein Quality Control.Reviews in cardiovascular medicine · 2024Review
- Insights into the dual nature of αB-crystallin chaperone activity from the p.P39L mutant at the N-terminal region.Scientific reports · 2024Article
- Roles of dystonin isoforms in the maintenance of neural, muscle, and cutaneous tissues.Anatomical science international · 2024Review
- S14-Phosphorylated RPN6 Mediates Proteasome Activation by PKA and Alleviates Proteinopathy.Circulation research · 2023Article
- A novel αB-crystallin R123W variant drives hypertrophic cardiomyopathy by promoting maladaptive calcium-dependent signal transduction.Frontiers in cardiovascular medicine · 2023Article
- Single cell sequencing revealed the mechanism of CRYAB in glioma and its diagnostic and prognostic value.Frontiers in immunology · 2023Article
- Desmin Knock-Out Cardiomyopathy: A Heart on the Verge of Metabolic Crisis.International journal of molecular sciences · 2022Article
- Article
- Cytoskeletal Protein Variants Driving Atrial Fibrillation: Potential Mechanisms of Action.Cells · 2022Review
- The molecular role of Sigmar1 in regulating mitochondrial function through mitochondrial localization in cardiomyocytes.Mitochondrion · 2022Article
- Monitoring Mitochondrial Morphology and Respiration in Doxorubicin-Induced Cardiomyopathy.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Insights on Human Small Heat Shock Proteins and Their Alterations in Diseases.Frontiers in molecular biosciences · 2022Review
- Baicalin Improves Cardiac Outcome and Survival by Suppressing Drp1-Mediated Mitochondrial Fission after Cardiac Arrest-Induced Myocardial Damage.Oxidative medicine and cellular longevity · 2021Article
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Authors and funding
10 authors at 1 institution in 1 country.
Shafiul AlamDepartment of Pathology and Translational Pathobiology Louisiana State University Health Sciences Center Shreveport LA.
Chowdhury S AbdullahDepartment of Pathology and Translational Pathobiology Louisiana State University Health Sciences Center Shreveport LA.
Richa AishwaryaDepartment of Molecular and Cellular Physiology Louisiana State University Health Sciences Center Shreveport LA.
Mahboob MorshedDepartment of Pathology and Translational Pathobiology Louisiana State University Health Sciences Center Shreveport LA.
Sadia S NituDepartment of Pathology and Translational Pathobiology Louisiana State University Health Sciences Center Shreveport LA.
Sumitra MiriyalaDepartment of Cellular Biology and Anatomy Louisiana State University Health Sciences Center Shreveport LA.
Manikandan PanchatcharamDepartment of Cellular Biology and Anatomy Louisiana State University Health Sciences Center Shreveport LA.
Christopher G KevilDepartment of Pathology and Translational Pathobiology Louisiana State University Health Sciences Center Shreveport LA.
A Wayne OrrDepartment of Pathology and Translational Pathobiology Louisiana State University Health Sciences Center Shreveport LA.
Md Shenuarin BhuiyanDepartment of Pathology and Translational Pathobiology Louisiana State University Health Sciences Center Shreveport LA.
Louisiana State University Health Sciences Center Shreveport · US
Funding
Stress Exacerbates Myocardial Ischemic Injury by Blocking Estrogen's Antidoxidant Protection in the Female HeartP20GM121307 · NIGMS · LOUISIANA STATE UNIV HSC SHREVEPORT · PI Tarek Magdy Mohamed · 2018 to 2026
$23.6MNck Adaptor Proteins in Atherogenic Endothelial ActivationR01HL133497 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI ORR, ANTHONY WAYNE · 2016 to 2024
$3.8MMatrix Signaling in Endothelial Cell DysfunctionR01HL098435 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI ORR, ANTHONY WAYNE · 2010 to 2020
$3.2MSigmar1 in lipid metabolismR01HL145753 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI BHUIYAN, MD. SHENUARIN · 2019 to 2023
$2.6MEphA2 signaling in atherosclerotic fibroproliferative remodelingR01HL141155 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI ORR, ANTHONY WAYNE · 2019 to 2022
$1.8MCSE regulation of vascular remodelingR01HL149264 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI KEVIL, CHRISTOPHER G · 2020 to 2023
$1.7MSigma-1 receptor and cardioprotectionR00HL122354 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI BHUIYAN, MD. SHENUARIN · 2015 to 2017
$747kAlcohol-LPP3 axis in ischemic strokeR21AA025744 · NIAAA · LOUISIANA STATE UNIV HSC SHREVEPORT · PI PANCHATCHARAM, MANIKANDAN · 2017 to 2018
$483kAlcohol mediated myocardial lysophosphatidic acid signalingR21AA026708 · NIAAA · LOUISIANA STATE UNIV HSC SHREVEPORT · PI PANCHATCHARAM, MANIKANDAN · 2020 to 2021
$383kSigma-1 receptor and cardioprotectionK99HL122354 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI BHUIYAN, MD. SHENUARIN · 2014 to 2015
$263kAmerican Heart Association-American Stroke Association 18POST34080495American Heart Association-American Stroke Association 20POST35210789 - CHOWDHURY ABDULLAHNHLBI NIH HHS K99 HL122354NHLBI NIH HHS R00 HL122354NHLBI NIH HHS R01 HL098435NHLBI NIH HHS R01 HL133497NHLBI NIH HHS R01 HL141155NHLBI NIH HHS R01 HL145753NHLBI NIH HHS R01 HL149264NIAAA NIH HHS R21 AA025744NIAAA NIH HHS R21 AA026708NIGMS NIH HHS P20 GM121307
Abstract
Background The mutated α-B-Crystallin (CryAB
Indexed as
Oxidative Phosphorylationalpha-Crystallin B ChainAnimalsCardiomyopathiesDesminDisease Models, AnimalMiceMice, TransgenicMitochondrial Dynamicsalpha-Crystallin B ChainDesmindesmin‐related myopathymitochondrial dynamicsmitochondrial respirationoxidative phosphorylationR120G‐αB‐crystallin
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LicenceCC BY-NC-ND
Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.