Evidence map›Paper›PMID 33208011›Full record

ArticleThe Journal of international medical research2020

Risk factors related to postpartum hepatic inflammation in pregnant women with chronic hepatitis B.

Lu Li, Huaibin Zou, Manman Xu, Shuang Li, Yunxia Zhu, Sujun Zheng, Zhongping Duan, Yu Chen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lu LiHepatology Center Department, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
Huaibin ZouHepatology Center Department, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
Manman XuHepatology Center Department, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
Shuang LiHepatology Center Department, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
Yunxia ZhuDepartment of Gynecology and Obstetrics, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
Sujun ZhengHepatology Center Department, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
Zhongping DuanHepatology Center Department, Beijing YouAn Hospital, Capital Medical University, Beijing, China.
Yu ChenHepatology Center Department, Beijing YouAn Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-0102-6478
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate liver function after pregnancy in women with chronic hepatitis B virus (HBV) and factors related to postpartum abnormalities.

methodsA total of 317 pregnant women were included in this study and 138 had an HBV DNA level. In this trial, the highest number and proportion of hepatitis B surface antigen-positive mothers with postpartum hepatic inflammation were at 1 month after delivery.

resultsBaseline liver function of postpartum women with hepatic inflammation was significantly higher than that in those before delivery. The rates of hepatitis B e-antigen (HBeAg)-positive status, baseline HBV DNA levels, gestational diabetes mellitus, and antiviral therapy during pregnancy were significantly higher in the hepatic inflammation group than in the control group. Among the 138 women who received antiviral therapy, 83 withdrew from antiviral therapy immediately after delivery and 55 continued antiviral therapy for at least 1 month after delivery. Multivariate logistic regression analysis showed that HBeAg-positivity and gestational diabetes mellitus were associated with hepatic inflammation after delivery. Postpartum hepatic inflammation occurred mostly at 1 month after delivery in pregnant women with HBV infection.

conclusionsClose monitoring of women with HBV during pregnancy is required, especially for those who are HBeAg-positive and have gestational diabetes mellitus.

Indexed as

Hepatitis BHepatitis B, ChronicPregnancy Complications, InfectiousAntiviral AgentsDNA, ViralFemaleHepatitis B e AntigensHepatitis B Surface AntigensHepatitis B virusHumansInflammationPostpartum PeriodPregnancyPregnant PeopleRisk FactorsAntiviral AgentsDNA, ViralHepatitis B e AntigensHepatitis B Surface Antigensantigenantiviral therapygestational diabetes mellitusHepatitis B viruspostpartum hepatic inflammationpregnancyrisk factor

Identifiers

PMID33208011
PMCPMC7683929
OpenAlexW3098555286

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.