Evidence map›Paper›PMID 33207819›Full record

ArticleMolecules (Basel, Switzerland)2020

Exploring the Proteomic Alterations from Untreated and Cryoablation and Irradiation Treated Giant Cell Tumors of Bone Using Liquid-Chromatography Tandem Mass Spectrometry.

Rashmi Madda, Chao-Ming Chen, Cheng-Fong Chen, Jir-You Wang, Po-Kuei Wu, Wei-Ming Chen

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rashmi MaddaDepartment of Orthopedics & Traumatology, Taipei Veterans General Hospital, Taipei City 112, Taiwan.ORCID 0000-0002-8962-8958
Chao-Ming ChenDepartment of Orthopedics & Traumatology, Taipei Veterans General Hospital, Taipei City 112, Taiwan.ORCID 0000-0001-8079-0062
Cheng-Fong ChenDepartment of Orthopedics & Traumatology, Taipei Veterans General Hospital, Taipei City 112, Taiwan.
Jir-You WangDepartment of Orthopedics & Traumatology, Taipei Veterans General Hospital, Taipei City 112, Taiwan.
Po-Kuei WuDepartment of Orthopedics & Traumatology, Taipei Veterans General Hospital, Taipei City 112, Taiwan.
Wei-Ming ChenDepartment of Orthopedics & Traumatology, Taipei Veterans General Hospital, Taipei City 112, Taiwan.
National Yang Ming Chiao Tung University · TW

Funding

Ministry of Science and Technology, Taiwan MOST- 108-2314-B-0101-041
6 · The paper itself

Abstract

Giant cell tumors of bone (GCT) are benign tumors that show a locally aggressive nature and affect bones' architecture. Recently, cryoablation and irradiation treatments have shown promising results in GCT patients with faster recovery and less recurrence and metastasis. Therefore, it became a gold standard surgical treatment for patients. Hence, we have compared GCT-untreated, cryoablation, and irradiation-treated samples to identify protein alterations using high-frequency liquid chromatography-electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS). Our label-free quantification analysis revealed a total of 107 proteins (

Indexed as

CryosurgeryProteomicsTandem Mass SpectrometryAdolescentChildChild, PreschoolChromatography, LiquidDown-RegulationFemaleGene OntologyGiant Cell Tumor of BoneHumansMaleMatrix Metalloproteinase 9Middle AgedNeoplasm ProteinsMatrix Metalloproteinase 9Neoplasm ProteinsTransforming Growth Factor betabiological samplescryoablationgiant cell tumor of boneirradiationliquid chromatographymass spectrometrymatrix metalloproteinasesproteomic analysisTGF-beta

Identifiers

PMID33207819
PMCPMC7696300
OpenAlexW3098163310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.