Evidence map›Paper›PMID 33207794›Full record

ArticleVaccines2020

Characterization of ShigETEC, a Novel Live Attenuated Combined Vaccine against Shigellae and ETEC.

Shushan Harutyunyan, Irene Neuhauser, Alexandra Mayer, Michael Aichinger, Valéria Szijártó, Gábor Nagy, Eszter Nagy, Petra Girardi, Frank J Malinoski, Tamás Henics

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Vaccines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05409196 (Phase 1 Two Stage Randomized, Double-blind, Placebo Controlled Dose- and Schedule Ranging Trial to Assess the Acute Safety, Tolerability, and Immunogenicity of a Live, Attenuated Shigella/ETEC Combination Vaccine Delivered Orally to Healthy Adults Age 18 to 45 Years Old), which is not on this map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05409196 phase1completednot on this map

Phase 1 Two Stage Randomized, Double-blind, Placebo Controlled Dose- and Schedule Ranging Trial to Assess the Acute Safety, Tolerability, and Immunogenicity of a Live, Attenuated Shigella/ETEC Combination Vaccine Delivered Orally to Healthy Adults Age 18 to 45 Years Old

TypeinterventionalSponsorEveliqure Biotechnologies GmbHRan2020 to 2021Enrolled84ConditionsDiarrheal Disease, Infectious, Gastrointestinal Disease, Reactive ArthritisArmsShigETEC live, attenuated, oral vaccine, Placebo
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 39 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Recent progress in enterotoxigenicInfection and immunity · 2025
    Review
  7. Shigellosis.Lancet (London, England) · 2025
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. A RecombinantInternational journal of molecular sciences · 2024
    Article
  14. Review
  15. Special Issue on EnterotoxigenicMicroorganisms · 2024
    Article
  16. International journal of molecular sciences · 2024
    Review
  17. Shigella-Controlled Human Infection Models: Current and Future Perspectives.Current topics in microbiology and immunology · 2024
    Review
  18. Article
  19. Article
  20. Development of themSphere · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Shushan HarutyunyanEveliqure Biotechnologies GmbH, Karl-Farkas-Gasse 22, 1030 Vienna, Austria.
Irene NeuhauserEveliqure Biotechnologies GmbH, Karl-Farkas-Gasse 22, 1030 Vienna, Austria.
Alexandra MayerEveliqure Biotechnologies GmbH, Karl-Farkas-Gasse 22, 1030 Vienna, Austria.
Michael AichingerEveliqure Biotechnologies GmbH, Karl-Farkas-Gasse 22, 1030 Vienna, Austria.
Valéria SzijártóEveliqure Biotechnologies GmbH, Karl-Farkas-Gasse 22, 1030 Vienna, Austria.
Gábor NagyEveliqure Biotechnologies GmbH, Karl-Farkas-Gasse 22, 1030 Vienna, Austria.
Eszter NagyEveliqure Biotechnologies GmbH, Karl-Farkas-Gasse 22, 1030 Vienna, Austria.
Petra GirardiEveliqure Biotechnologies GmbH, Karl-Farkas-Gasse 22, 1030 Vienna, Austria.
Frank J MalinoskiEveliqure Biotechnologies GmbH, Karl-Farkas-Gasse 22, 1030 Vienna, Austria.
Tamás HenicsEveliqure Biotechnologies GmbH, Karl-Farkas-Gasse 22, 1030 Vienna, Austria.
Institute of Molecular Biotechnology · AT

Funding

Österreichische Forschungsförderungsgesellschaft 845251, 851641, 858478 and 865576
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cross-protectionETECheat-labile toxinheat-stable toxinnon-invasiveroughShigellavaccine

Identifiers

PMID33207794
PMCPMC7712393
OpenAlexW3104998054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.