Evidence map›Paper›PMID 33207767›Full record

ArticleMolecules (Basel, Switzerland)2020

Molecular Modeling, Synthesis and Biological Evaluation of

Dima A Sabbah, Shaima' E Hasan, Reema Abu Khalaf, Sanaa K Bardaweel, Rima Hajjo, Khalid M Alqaisi, Kamal A Sweidan, Aya M Al-Zuheiri

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Molecules (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Molecules (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dima A SabbahDepartment of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, P.O. Box 130, Amman 11733, Jordan.
Shaima' E HasanDepartment of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, P.O. Box 130, Amman 11733, Jordan.
Reema Abu KhalafDepartment of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, P.O. Box 130, Amman 11733, Jordan.
Sanaa K BardaweelDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Jordan, Amman 11942, Jordan.ORCID 0000-0002-4823-0708
Rima HajjoDepartment of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, P.O. Box 130, Amman 11733, Jordan.
Khalid M AlqaisiDepartment of Medical Laboratory Sciences, Faculty of Allied Medical Sciences, Al-Ahliyya Amman University, Amman 19328, Jordan.
Kamal A SweidanDepartment of Chemistry, The University of Jordan, Amman 11942, Jordan.
Aya M Al-ZuheiriDepartment of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, P.O. Box 130, Amman 11733, Jordan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of phosphatidylinositol 3-kinase (PI3Kα) in cancer development has accentuated its significance as a potential target for anticancer drug design. Twenty one derivatives of

Indexed as

Models, MolecularAntineoplastic AgentsCaco-2 CellsGene Expression Regulation, NeoplasticHCT116 CellsHumansInhibitory Concentration 50Molecular Docking SimulationPhosphatidylinositol 3-KinasesPrincipal Component AnalysisProtein Kinase InhibitorsQuinolonesAntineoplastic AgentsPhosphatidylinositol 3-KinasesProtein Kinase InhibitorsQuinolonesAKTanticancercolon cancerdockingPI3Kαquinolone-3-carboxamide

Identifiers

PMID33207767
PMCPMC7698136

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.