Evidence map›Paper›PMID 33207759›Full record

ArticleTropical medicine and infectious disease2020

Risk Factors for Elevated Serum Lipopolysaccharide in Acute Dengue and Association with Clinical Disease Severity.

N L Ajantha Shyamali, Sameera D Mahapatuna, Laksiri Gomes, Ananda Wijewickrama, Graham S Ogg, Gathsaurie Neelika Malavige

Open access · goldAbstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

N L Ajantha ShyamaliCentre for Dengue Research, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka.ORCID 0000-0002-3403-3308
Sameera D MahapatunaCentre for Dengue Research, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka.
Laksiri GomesCentre for Dengue Research, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka.
Ananda WijewickramaNational Institute of Infectious Diseases, Angoda 10620, Sri Lanka.
Graham S OggCentre for Dengue Research, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka.
Gathsaurie Neelika MalavigeCentre for Dengue Research, University of Sri Jayewardenepura, Nugegoda 10250, Sri Lanka.
University of Sri Jayewardenepura · LKNational Hospital of Sri Lanka · LK

Funding

Centre for Dengue Research, University of Sri Jayewardenepura noneMedical Research Council G116/150Medical Research Council MC_U137881017Medical Research Council MC_UU_00008/5Medical Research Council MC_UU_12010/5National Science Foundation, LK RPHS/2016/D-06
6 · The paper itself

Abstract

Although serum lipopolysaccharide (LPS) was shown to associate with development of severe dengue, the reasons for high LPS and its subsequent involvement in disease pathogenesis are not known. We assessed serum LPS, C-reactive protein (CRP), and procalcitonin in patients with acute dengue fever (DF = 129) and dengue haemorrhagic fever (DHF = 64) and correlated these observations with the presence of comorbid illnesses, and clinical disease severity. Serum LPS levels were significantly (

Indexed as

CRPdenguelipopolysaccharidemetabolic diseasessevere dengue

Identifiers

PMID33207759
PMCPMC7709576
OpenAlexW3100669905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.