Evidence map›Paper›PMID 33207612›Full record

ReviewNutrients2020

Food Addiction and Psychosocial Adversity: Biological Embedding, Contextual Factors, and Public Health Implications.

David A Wiss, Nicole Avena, Mark Gold

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. A meta-analysis assessing reliability of the Yale Food Addiction Scale: Implications for compulsive eating and obesity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Environmental Influences on Food Addiction and Cardiometabolic Profiles in Law Enforcement Officers.International journal of environmental research and public health · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
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  14. Food inequity and insecurity and MASLD: burden, challenges, and interventions.Nature reviews. Gastroenterology & hepatology · 2024
    Review
  15. Article
  16. Review
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

David A WissFielding School of Public Health, University of California Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0003-1788-7368
Nicole AvenaDepartment of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Mark GoldSchool of Medicine, Washington University in St. Louis, St. Louis, MO 63130, USA.
Princeton University · USUniversity of California, Los Angeles · USWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of stress, trauma, and adversity particularly early in life has been identified as a contributing factor in both drug and food addictions. While links between traumatic stress and substance use disorders are well documented, the pathways to food addiction and obesity are less established. This review focuses on psychosocial and neurobiological factors that may increase risk for addiction-like behaviors and ultimately increase BMI over the lifespan. Early childhood and adolescent adversity can induce long-lasting alterations in the glucocorticoid and dopamine systems that lead to increased addiction vulnerability later in life. Allostatic load, the hypothalamic-pituitary-adrenal axis, and emerging data on epigenetics in the context of biological embedding are highlighted. A conceptual model for food addiction is proposed, which integrates data on the biological embedding of adversity as well as upstream psychological, social, and environmental factors. Dietary restraint as a feature of disordered eating is discussed as an important contextual factor related to food addiction. Discussion of various public health and policy considerations are based on the concept that improved knowledge of biopsychosocial mechanisms contributing to food addiction may decrease stigma associated with obesity and disordered eating behavior.

Indexed as

Life Change EventsPublic HealthAdolescentAdultChildDiet TherapyDopamineEpigenomicsFood AddictionGlucocorticoidsHumansHypothalamo-Hypophyseal SystemObesityPituitary-Adrenal SystemStress, PsychologicalDopamineGlucocorticoidsadverse childhood experiencebiopsychosocialdopamineearly life adversityeating disorderepigeneticsfood addictionobesitystresstrauma

Identifiers

PMID33207612
PMCPMC7698089
OpenAlexW3102674488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.