Evidence map›Paper›PMID 33207582›Full record

ArticlePathogens (Basel, Switzerland)2020

Genomic Analysis of Oral Lichen Planus and Related Oral Microbiome Pathogens.

Evelyn F Zhong, Andrea Chang, Andres Stucky, Xuelian Chen, Tarun Mundluru, Mohammad Khalifeh, Parish P Sedghizadeh

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. The Role of TRPV1/CGRP Pathway Activated byInternational journal of molecular sciences · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Comprehensive Insight into Lichen Planus Immunopathogenesis.International journal of molecular sciences · 2023
    Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Frontiers in microbiology · 2022
    Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Evelyn F ZhongDiagnostic Sciences, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA 90089, USA.
Andrea ChangDiagnostic Sciences, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA 90089, USA.
Andres StuckyDiagnostic Sciences, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA 90089, USA.
Xuelian ChenDiagnostic Sciences, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA 90089, USA.
Tarun MundluruDiagnostic Sciences, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA 90089, USA.
Mohammad KhalifehDiagnostic Sciences, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA 90089, USA.
Parish P SedghizadehDiagnostic Sciences, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA 90089, USA.
University of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral lichen planus (OLP) is a common chronic inflammatory disease affecting the oral mucosa. The pathogenesis of OLP is incompletely understood but is thought to be related to the immune system. As the oral cavity is a major reservoir and transmission gateway for bacteria, viruses, and fungi, the microbial composition of the oral cavity could play a role in the pathogenesis of OLP. However, limited by analytic technology and knowledge of the microbial community in the oral cavity, it is not yet clear which pathogens are associated with OLP. Next generation sequencing (NGS) is a powerful tool to identify pathogens for many infectious diseases. In this study, we compared the host cell gene expression profiles and the microbial profiles between OLP patients and matched healthy individuals. We identified the activation of the hepatocyte nuclear factor alpha (HNF4A) network in OLP patients and potential pathogens, including

Indexed as

HNF4Alichen planus pathogenesismicrobiomenext generation sequencePrevotella denticolaT-helper cell

Identifiers

PMID33207582
PMCPMC7697643
OpenAlexW3106104677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.