SynthesisPloS one2020
Effects of music therapy on depression: A meta-analysis of randomized controlled trials.
Synthesis in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 4 syntheses or guidelines pooled it, 131 citations in OpenAlex.
- The safety and effectiveness of music medicine as an intervention for depression: A systematic evaluation and re-evaluation.Brain and behavior · 2024Pooled it
- Effect of music therapy on anxiety and depression in breast cancer patients: systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Musicotherapy mobile applications: what level of evidence and potential role in psychiatric care? A systematic review.Frontiers in psychiatry · 2024Pooled it
- Group-based active artistic interventions for adults with primary anxiety and depression: a systematic review.BMJ open · 2023Pooled it
- Preparing for future pandemics: enhancing serotonin activation and interpersonal warmth through music therapy to aid in adolescent depression recovery post-COVID-19: a randomized controlled trial.BMC complementary medicine and therapies · 2026Trial
- High-frequency vs. low-frequency MIDI-assisted group music therapy in psychiatric inpatients: A randomized controlled trial.PloS one · 2026Trial
- Trial
- Psychophysiological effects of music on sadness in participants with and without depressive symptoms.BMC complementary medicine and therapies · 2025Trial
- Trial
- Effects of music therapy as an alternative treatment on depression in children and adolescents with ADHD by activating serotonin and improving stress coping ability.BMC complementary medicine and therapies · 2023Trial
- Music therapy for mental health in children and adolescents: a systematic review and meta-analysis of randomized trials.Child and adolescent psychiatry and mental health · 2026Review
- The Therapeutic Home Environment for Chronic Diseases: A Transdisciplinary Ecosystem for Achieving Migraine Freedom and Managing Comorbid Anxiety, Insomnia, and Chronic Pain.Healthcare (Basel, Switzerland) · 2026Article
- Effectiveness of Music Therapy on Utilization Outcomes among Surgical Patients with Mental Health Conditions: A Propensity-Score Matched Cohort Study.Journal of integrative and complementary medicine · 2026Article
- Effects of a piano music listening intervention on depression, academic burnout, and mindfulness: evidence from a randomized controlled trial among Chinese university students.Frontiers in psychology · 2026Article
- A scoping review of music-based digital therapeutics for stress, anxiety, and depression.Frontiers in human neuroscience · 2026Review
- Clinical and psychological changes associated with music listening in haemodialysis patients: A prospective study.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2026Article
- Varied effectiveness of outpatient rehabilitation interventions in reducing long-term complications following childhood brain tumours: a systematic review.Frontiers in rehabilitation sciences · 2026Article
- Understanding emotional responses to music using machine learning: evidence from a public dataset.Frontiers in psychology · 2026Article
- Psychophysiological effects of low-frequency sound mediated by room size, room shape, and stimulus duration.Frontiers in cognition · 2026Article
- Development and usability evaluation of an audio-based cognitive behavioral therapy mobile app for depression in hemodialysis patients.BMC psychology · 2025Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to determine and compare the effects of music therapy and music medicine on depression, and explore the potential factors associated with the effect.
methodsPubMed (MEDLINE), Ovid-Embase, the Cochrane Central Register of Controlled Trials, EMBASE, Web of Science, and Clinical Evidence were searched to identify studies evaluating the effectiveness of music-based intervention on depression from inception to May 2020. Standardized mean differences (SMDs) were estimated with random-effect model and fixed-effect model.
resultsA total of 55 RCTs were included in our meta-analysis. Music therapy exhibited a significant reduction in depressive symptom (SMD = -0.66; 95% CI = -0.86 to -0.46; P<0.001) compared with the control group; while, music medicine exhibited a stronger effect in reducing depressive symptom (SMD = -1.33; 95% CI = -1.96 to -0.70; P<0.001). Among the specific music therapy methods, recreative music therapy (SMD = -1.41; 95% CI = -2.63 to -0.20; P<0.001), guided imagery and music (SMD = -1.08; 95% CI = -1.72 to -0.43; P<0.001), music-assisted relaxation (SMD = -0.81; 95% CI = -1.24 to -0.38; P<0.001), music and imagery (SMD = -0.38; 95% CI = -0.81 to 0.06; P = 0.312), improvisational music therapy (SMD = -0.27; 95% CI = -0.49 to -0.05; P = 0.001), music and discuss (SMD = -0.26; 95% CI = -1.12 to 0.60; P = 0.225) exhibited a different effect respectively. Music therapy and music medicine both exhibited a stronger effects of short and medium length compared with long intervention periods.
conclusionsA different effect of music therapy and music medicine on depression was observed in our present meta-analysis, and the effect might be affected by the therapy process.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.