Evidence map›Paper›PMID 33206342›Full record

ArticleProbiotics and antimicrobial proteins2021

Effects of a Potential Probiotic Strain Lactobacillus gasseri ATCC 33323 on Helicobacter pylori-Induced Inflammatory Response and Gene Expression in Coinfected Gastric Epithelial Cells.

Mahdieh Yarmohammadi, Abbas Yadegar, Maryam Tajabadi Ebrahimi, Mohammad Reza Zali

Abstract read
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In one paragraph

Article in Probiotics and antimicrobial proteins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 35 citations in OpenAlex.

  1. Effect of Probiotic-Assisted Eradication ofBioMed research international · 2022
    Trial
  2. Activity ofVirulence · 2026
    Article
  3. Article
  4. Beyond the Stomach: Exploring the Role ofExpert reviews in molecular medicine · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Heliyon · 2023
    Article
  14. Article
  15. Review
  16. Article
  17. The Effects ofBioMed research international · 2023
    Article
  18. Review
  19. Article
  20. [Isolation, identification and safety evaluation ofNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Mahdieh YarmohammadiDepartment of Biology, Faculty of Sciences, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Abbas YadegarFoodborne and Waterborne Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran. a.yadegar@sbmu.ac.ir.ORCID 0000-0002-2135-7581
Maryam Tajabadi EbrahimiDepartment of Biology, Faculty of Sciences, Central Tehran Branch, Islamic Azad University, Tehran, Iran. m.tajabadi@iauctb.ac.ir.
Mohammad Reza ZaliGastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Islamic Azad University Central Tehran Branch · IRResearch Institute for Endocrine Sciences · IRShahid Beheshti University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present study, we aimed to investigate the modulatory effects of a potential probiotic bacterium Lactobacillus gasseri ATCC 33323 on Helicobacter pylori-induced inflammatory response and gene expression in human gastric adenocarcinoma (AGS) cell line. The gastric epithelial cells were coinfected with a collection of H. pylori clinical strains alone or in combination with L. gasseri at a multiplicity of infection (MOI) of 1:100 for each bacterium, and incubated for different time points of 3, 6, and 12 h. IL-8 secretion from coinfected AGS cells after incubation at each time point was measured by an enzyme-linked immunosorbent assay (ELISA). The mRNA expression of IL-8, Bcl-2, β-catenin, integrin α

Indexed as

CoinfectionHelicobacter pyloriLactobacillus gasseriProbioticsbeta CateninCell Line, TumorEpithelial CellsGene ExpressionHumansIntegrinsInterleukin-8Proto-Oncogene Proteins c-bcl-2RNA, Messengerbeta CateninIntegrinsInterleukin-8Proto-Oncogene Proteins c-bcl-2RNA, MessengerCoinfectionHelicobacter pyloriIL-8InflammationLactobacillus gasseri ATCC 33323Probiotic

Identifiers

PMID33206342
OpenAlexW3101130025

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.